STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP0969Similar to Mycobacterium tuberculosis CDC1551 GTP-binding elongation factor family protein MT1202 TR:AAK45459 (EMBL:AE006997) (628 aa) fasta scores: E(): 6.7e-148, 67.88% id in 629 aa, and to Escherichia coli GTP-binding protein TypA/BipA TypA or BipA or B3871 SW:TYPA_ECOLI (P32132) (591 aa) fasta scores: E(): 3.3e-58, 46.49% id in 613 aa. (636 aa)    
Predicted Functional Partners:
DIP0970
Putative secreted protein; Similar to Mycobacterium tuberculosis hypothetical 66.1 kDa protein LpqW or Rv1166 or MTV005.02 TR:O50422 (EMBL:AL010186) (635 aa) fasta scores: E(): 4.6e-29, 32.02% id in 381 aa.
  
    0.879
mshB
Conserved hypothetical protein; Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2- deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.
       0.831
DIP0972
Putative membrane protein; No significant database matches.
       0.777
DIP1239
Putative helicase; Similar to Mycobacterium tuberculosis probable helicase HelY or Rv2092c or MT2153 or MTCY49.30c SWALL:HELY_MYCTU (SWALL:Q10701) (906 aa) fasta scores: E(): 4.5e-69, 48.87% id in 933 aa, and to Synechocystis sp antiviral protein Ski2 or SLR0451 SWALL:P74686 (EMBL:D90917) (1006 aa) fasta scores: E(): 2.3e-27, 29.42% id in 1040 aa.
      
 0.762
rplA
50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
   
    0.698
fdxA
Ferredoxin; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
       0.694
engA
Putative GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
  
  
 0.687
DIP0974
Putative aminotransferase; Similar to Mycobacterium leprae possible aminotransferase ML1488 TR:Q9CBX8 (EMBL:AL583922) (367 aa) fasta scores: E(): 3.9e-81, 60.44% id in 364 aa. Possible alternative transcription start in the second residue.
       0.653
guaA
GMP synthase [glutamine-hydrolysing]; Catalyzes the synthesis of GMP from XMP.
  
  
 0.646
DIP0975
Similar to, although shorter than, Mycobacterium tuberculosis CDC1551 RNA pseudouridylate synthase family protein MT3399 TR:AAK47742 (EMBL:AE007148) (305 aa) fasta scores: E(): 3.5e-23, 37.33% id in 233 aa, and similar to Escherichia coli ribosomal large subunit pseudouridine synthase A RluR or B0058 SW:RLUA_ECOLI (P39219) (218 aa) fasta scores: E(): 1.8e-07, 26.76% id in 213 aa.
  
   0.642
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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