Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DIP0975Similar to, although shorter than, Mycobacterium tuberculosis CDC1551 RNA pseudouridylate synthase family protein MT3399 TR:AAK47742 (EMBL:AE007148) (305 aa) fasta scores: E(): 3.5e-23, 37.33% id in 233 aa, and similar to Escherichia coli ribosomal large subunit pseudouridine synthase A RluR or B0058 SW:RLUA_ECOLI (P39219) (218 aa) fasta scores: E(): 1.8e-07, 26.76% id in 213 aa. (243 aa)    
Predicted Functional Partners:
DIP0976
Putative membrane protein; No significant database matches.
       0.759
DIP0974
Putative aminotransferase; Similar to Mycobacterium leprae possible aminotransferase ML1488 TR:Q9CBX8 (EMBL:AL583922) (367 aa) fasta scores: E(): 3.9e-81, 60.44% id in 364 aa. Possible alternative transcription start in the second residue.
       0.735
fdxA
Ferredoxin; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
   
   0.699
DIP0970
Putative secreted protein; Similar to Mycobacterium tuberculosis hypothetical 66.1 kDa protein LpqW or Rv1166 or MTV005.02 TR:O50422 (EMBL:AL010186) (635 aa) fasta scores: E(): 4.6e-29, 32.02% id in 381 aa.
 
     0.644
DIP0972
Putative membrane protein; No significant database matches.
       0.615
rsfS
Conserved hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
  
 
 0.612
rplQ
Similar to Mycobacterium leprae 50S ribosomal protein L17 RplQ or ML1956 or MLCB1222.26c SW:RL17_MYCLE (Q9X797) (170 aa) fasta scores: E(): 3.1e-26, 58.86% id in 158 aa.
  
   0.611
DIP0969
Similar to Mycobacterium tuberculosis CDC1551 GTP-binding elongation factor family protein MT1202 TR:AAK45459 (EMBL:AE006997) (628 aa) fasta scores: E(): 6.7e-148, 67.88% id in 629 aa, and to Escherichia coli GTP-binding protein TypA/BipA TypA or BipA or B3871 SW:TYPA_ECOLI (P32132) (591 aa) fasta scores: E(): 3.3e-58, 46.49% id in 613 aa.
  
 
 0.611
rplU
50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
   
   0.604
rplC
50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
   
 
 0.597
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.