STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dapDPutative succinyltransferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. (324 aa)    
Predicted Functional Partners:
DIP0981
Putative succinyltransferase; Similar to Mycobacterium tuberculosis CDC1551 tetrahydrodipicolinate N-succinyltransferase, putative MT1239 TR:AAK45496 (EMBL:AE007001) (317 aa) fasta scores: E(): 3.2e-46, 46.53% id in 303 aa, and C-terminal region to Corynebacterium glutamicum tetrahydrodipicolinate succinylase DapD TR:O69283 (EMBL:AJ004934) (230 aa) fasta scores: E(): 1.6e-28, 45.2% id in 219 aa. Similar also to DIP0979 (45.614% identity in 285 aa overlap).
 
  
 
0.959
dapB
Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
  
 
 0.959
argD
Similar to Corynebacterium glutamicum acetylornithine aminotransferase ArgD SWALL:ARGD_CORGL (SWALL:Q59282) (389 aa) fasta scores: E(): 2.9e-98, 65.21% id in 391 aa, and to Mycobacterium tuberculosis acetylornithine aminotransferase ArgD or Rv1655 or MT1693 or MTCY06H11.20 SWALL:ARGD_MYCTU (SWALL:P94990) (400 aa) fasta scores: E(): 5.2e-74, 50.12% id in 405 aa; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
    
 0.908
aroP2
Similar to Corynebacterium glutamicum aromatic amino acid transport protein AroP SW:AROP_CORGL (Q46065) (463 aa) fasta scores: E(): 6.2e-118, 74.27% id in 447 aa, and to Escherichia coli gaba permease GabP or B2663 SW:GABP_ECOLI (P25527) (466 aa) fasta scores: E(): 6.2e-59, 41.03% id in 446 aa. Possible duplication of DIP0978 (57.395% identity in 453 aa overlap).
       0.780
dapE
Similar to Corynebacterium glutamicum succinyl-diaminopimelate desuccinylase DapE SW:DAPE_CORGL (Q59284) (369 aa) fasta scores: E(): 1.2e-87, 61.11% id in 360 aa, and to Escherichia coli succinyl-diaminopimelate desuccinylase DapE or MsgB or B2472 SW:DAPE_ECOLI (P24176) (375 aa) fasta scores: E(): 3.8e-09, 28.53% id in 354 aa.
 
   
 0.775
DIP0974
Putative aminotransferase; Similar to Mycobacterium leprae possible aminotransferase ML1488 TR:Q9CBX8 (EMBL:AL583922) (367 aa) fasta scores: E(): 3.9e-81, 60.44% id in 364 aa. Possible alternative transcription start in the second residue.
 
  
 0.745
guaA
GMP synthase [glutamine-hydrolysing]; Catalyzes the synthesis of GMP from XMP.
   
  
 0.650
glnD
Similar to Corynebacterium glutamicum [protein-PII] uridylyltransferase GlnD SW:GLND_CORGL (Q9X706) (692 aa) fasta scores: E(): 7.1e-126, 52.6% id in 709 aa, and to Escherichia coli [protein-PII] uridylyltransferase GlnD or B0167 SW:GLND_ECOLI (P27249) (890 aa) fasta scores: E(): 1.1e-05, 25.76% id in 555 aa. Note It might have two alternative start codons at residues 3 or 4.
     
 0.630
aroP1
Similar to Corynebacterium glutamicum aromatic amino acid transport protein AroP SW:AROP_CORGL (Q46065) (463 aa) fasta scores: E(): 1.1e-91, 56.16% id in 454 aa. Possible duplication of DIP0980 (57.395% identity in 453 aa overlap).
       0.610
murB
Putative peptidoglycan synthesis related protein; Cell wall formation.
 
   
 0.592
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.