STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP0988Similar to Micromonospora griseorubida mycinamicin-resistance protein MyrA SW:MYRA_MICGR (P37000) (295 aa) fasta scores: E(): 2.8e-31, 39.51% id in 286 aa, and to Streptomyces fradiae tylosin resistance protein TlrB TR:Q9ZHQ6 (EMBL:AF055922) (280 aa) fasta scores: E(): 2.4e-30, 37.82% id in 267 aa. (289 aa)    
Predicted Functional Partners:
DIP0987
Conserved hypothetical protein; Similar to C-terminal region of Streptomyces coelicolor conserved hypothetical protein SCP8.08 TR:Q9FBL3 (EMBL:AL390975) (74 aa) fasta scores: E(): 8.5e-11, 60.37% id in 53 aa.
       0.778
DIP0985
Conserved hypothetical protein; Similar to Streptomyces coelicolor hypothetical 34.0 kDa protein SCD95A.25c TR:Q9KXU9 (EMBL:AL357432) (314 aa) fasta scores: E(): 2.9e-29, 47.67% id in 258 aa, and to Methanothermobacter thermautotrophicus dolichyl-phosphate mannose synthase related protein MTH374 TR:O26474 (EMBL:AE000823) (291 aa) fasta scores: E(): 1.4e-08, 31.89% id in 254 aa.
  
    0.657
dapE
Similar to Corynebacterium glutamicum succinyl-diaminopimelate desuccinylase DapE SW:DAPE_CORGL (Q59284) (369 aa) fasta scores: E(): 1.2e-87, 61.11% id in 360 aa, and to Escherichia coli succinyl-diaminopimelate desuccinylase DapE or MsgB or B2472 SW:DAPE_ECOLI (P24176) (375 aa) fasta scores: E(): 3.8e-09, 28.53% id in 354 aa.
       0.652
DIP0983
Conserved hypothetical protein; Similar in its N-terminal region to Corynebacterium glutamicum ORF2 protein TR:Q46063 (EMBL:X81379) (211 aa) fasta scores: E(): 2.5e-63, 76.66% id in 210 aa, and to Streptomyces coelicolor hypothetical 27.5 kDa protein SCP8.03 TR:Q9FBL8 (EMBL:AL390975) (252 aa) fasta scores: E(): 7.5e-60, 64.08% id in 245 aa; Belongs to the LOG family.
       0.652
folP
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
       0.652
DIP0986
Putative secreted protein; Similar to, although shorter than, Streptomyces coelicolor putative secreted protein SCP8.05 TR:Q9FBL6 (EMBL:AL390975) (119 aa) fasta scores: E(): 1.1, 32.09% id in 81 aa.
       0.652
DIP0981
Putative succinyltransferase; Similar to Mycobacterium tuberculosis CDC1551 tetrahydrodipicolinate N-succinyltransferase, putative MT1239 TR:AAK45496 (EMBL:AE007001) (317 aa) fasta scores: E(): 3.2e-46, 46.53% id in 303 aa, and C-terminal region to Corynebacterium glutamicum tetrahydrodipicolinate succinylase DapD TR:O69283 (EMBL:AJ004934) (230 aa) fasta scores: E(): 1.6e-28, 45.2% id in 219 aa. Similar also to DIP0979 (45.614% identity in 285 aa overlap).
       0.442
fas
Putative fatty acid synthase; Similar to the N-terminal region of Corynebacterium ammoniagenes fatty acid synthase Fas TR:Q04846 (EMBL:X64795) (3104 aa) fasta scores: E(): 0, 61.33% id in 3018 aa, and to the full length of Mycobacterium tuberculosis fatty acid synthase Rv2524c TR:AAK46907 (EMBL:Z83863) (3069 aa) fasta scores: E(): 1e-197, 51.37% id in 3083 aa, and of Corynebacterium glutamicum 3-oxoacyl-(acyl-carrier-protein) synthase CGL2495 SWALL:Q8NMS0 (EMBL:AP005281) (2993 aa) fasta scores: E(): 0, 67.35% id in 3008 aa.
     
 0.433
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.