STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glgCGlucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (427 aa)    
Predicted Functional Partners:
DIP0991
Putative glycosyltransferase; Similar to Mycobacterium tuberculosis CDC1551 glycosyl transferase MT1250 TR:AAK45507 (EMBL:AE007001) (387 aa) fasta scores: E(): 2.9e-91, 60.72% id in 387 aa, and to Bacillus subtilis spore coat protein SA CotSA SW:CTSA_BACSU (P46915) (377 aa) fasta scores: E(): 1.6e-13, 24.37% id in 402 aa.
 
  
 0.997
DIP1552
Putative glycogen phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
 
 
 0.997
glgB
1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
 
  
 0.990
DIP0902
Putative hydrolase; Similar to the C-terminal regions of Thermotoga maritima pullulanase precursor PulA or TM1845 SW:PULA_THEMA (O33840) (843 aa) fasta scores: E(): 3.3e-67, 36.72% id in 610 aa, and of Klebsiella pneumoniae pullulanase precursor PulA SW:PULA_KLEPN (P07206) (1090 aa) fasta scores: E(): 1.2e-20, 28.94% id in 615 aa; Belongs to the glycosyl hydrolase 13 family.
 
 
 0.969
DIP1726
Putative glucanotransferase; Similar to Mycobacterium tuberculosis 4-alpha-glucanotransferase MalQ or Rv1781c or MT1831 or MTV049.03c SW:MALQ_MYCTU (O53932) (724 aa) fasta scores: E(): 7.8e-73, 45.87% id in 728 aa, and to Escherichia coli 4-alpha-glucanotransferase MalQ or MalA or B3416 SW:MALQ_ECOLI (P15977) (694 aa) fasta scores: E(): 1.2e-29, 28.48% id in 660 aa.
 
  
 0.967
DIP0862
Putative urydyltransferase; Similar to Mycobacterium tuberculosis CDC1551 UTP--glucose-1-phosphate uridylyltransferase MT1022 TR:AAK45269 (EMBL:AE006986) (306 aa) fasta scores: E(): 3.2e-65, 64.8% id in 287 aa, and to Bacillus subtilis UTP--glucose-1-phosphate uridylyltransferase GtaB SW:GTAB_BACSU (Q05852) (292 aa) fasta scores: E(): 1.4e-32, 40.67% id in 295 aa.
     
 0.959
DIP1966
Putative glycosyltransferase; Similar to Schizosaccharomyces pombe alpha,alpha-trehalose-phosphate synthase [UDP-forming] TPS1 SW:TPS1_SCHPO (P40387) (513 aa) fasta scores: E(): 7e-55, 36.68% id in 477 aa, and to Mycobacterium tuberculosis alpha,alpha-trehalose-phosphate synthase Rv3490 TR:O06353 (EMBL:Z95390) (500 aa) fasta scores: E(): 3.1e-98, 55.18% id in 482 aa.
     
 0.959
glgX
Glycogen operon protein; Similar to Mycobacterium tuberculosis glycogen operon protein GlgX homolog or Rv1564c or MT1615 or MTCY48.01 SW:GLGX_MYCTU (Q10767) (721 aa) fasta scores: E(): 5.5e-205, 69.12% id in 706 aa, and to Escherichia coli glycogen operon protein GlgX or GlyX or B3431 SW:GLGX_ECOLI (P15067) (657 aa) fasta scores: E(): 8.1e-87, 46.38% id in 664 aa; Belongs to the glycosyl hydrolase 13 family.
 
  
 0.940
pgm
Phosphoglucomutase; Similar to Escherichia coli phosphoglucomutase Pgm SW:PGMU_ECOLI (P36938) (546 aa) fasta scores: E(): 2.7e-133, 62.5% id in 544 aa, and to Mycobacterium tuberculosis hypothetical protein Rv3068c TR:P95090 (EMBL:Z83866) (547 aa) fasta scores: E(): 7e-150, 69.76% id in 549 aa.
    
 0.939
glgE
Putative alpha-amylase (glucanase); Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.
  
  
 0.882
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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