STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
tatBPutative Sec-independent twin-arginine translocase system protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. (147 aa)    
Predicted Functional Partners:
tatC
Sec-independent twin-arginine translocase system protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
 
 0.993
DIP0995
Similar to Mycobacterium leprae hypothetical protein ML1077 TR:Q9CCA5 (EMBL:AL583920) (139 aa) fasta scores: E(): 8e-09, 40.35% id in 114 aa.
 
    0.943
guaA
GMP synthase [glutamine-hydrolysing]; Catalyzes the synthesis of GMP from XMP.
  
    0.875
tatA
Sec-independent twin-arginine translocase system protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
    
 0.863
secE
Putative translocase protein; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
  
  
 0.834
secF
Putative protein export membrane protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
 
  
 0.813
secA2
Putative preprotein translocase; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
      
 0.743
DIP1848
Putative membrane protein; Similar to Mycobacterium tuberculosis hypothetical protein Rv1343c SW:YD43_MYCTU (Q11013) (126 aa) fasta scores: E(): 6.9e-12, 47.61% id in 84 aa, and to Mycobacterium leprae hypothetical protein ML1177 SW:YD43_MYCLE (P54134) (126 aa) fasta scores: E(): 1.5e-11, 46.42% id in 84 aa.
  
     0.727
DIP0639
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 45.7 kDa protein Rv3311 or MTV016.10 TR:O53362 (EMBL:AL021841) (420 aa) fasta scores: E(): 1.4e-25, 34.05% id in 417 aa.
  
     0.726
DIP0567
Similar to Mycobacterium leprae hypothetical protein ML0370 TR:Q9CCV6 (EMBL:AL583918) (289 aa) fasta scores: E(): 6.4e-34, 42.46% id in 252 aa.
  
     0.711
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.