STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1011Similar to putative aldose 1-epimerases e.g. Escherichia coli O157:H7 putative aldose-1-epimerase ECS4802 TR:BAB38225 (EMBL:AP002567) (300 aa) fasta scores: E(): 3.1e-21, 29.09% id in 299 aa, and to Escherichia coli hypothetical protein YihR or B3879 SW:YIHR_ECOLI (P32139) (308 aa) fasta scores: E(): 7.7e-21, 30.35% id in 280 aa, and to Salmonella typhimurium putative aldose-1-epimerase YihR TR:Q9L7R7 (EMBL:AF220438) (280 aa) fasta scores: E(): 1.1e-13, 29.53% id in 281 aa. Contains weak match to PFAM:PF01263 Aldose 1-epimerase E: 0.089. (305 aa)    
Predicted Functional Partners:
galK
Galactokinase; Similar to Streptomyces lividans galactokinase GalK SW:GAL1_STRLI (P13227) (397 aa) fasta scores: E(): 1.3e-27, 36.45% id in 384 aa, and to Homo sapiens galactokinase GalK1 or GalK SW:GAL1_HUMAN (P51570) (392 aa) fasta scores: E(): 3e-23, 38.29% id in 410 aa, and to Escherichia coli galactokinase GalK or GalA or B0757 or Z0927 or ECS0785 SW:GAL1_ECOLI (P06976) (381 aa) fasta scores: E(): 1e-11, 32.08% id in 399 aa; Belongs to the GHMP kinase family. GalK subfamily.
 
 0.988
DIP1674
Hypothetical protein; Very low similarity to Homo sapiens galactokinase GalK1 or GalK SW:GAL1_HUMAN (P51570) blast scores: E(): 3e-05, score: 51 24% id.
  
 0.964
ppgK
Polyphosphate glucokinase; Similar to Mycobacterium tuberculosis polyphosphate glucokinase PpgK or Rv2702 or MT2776 or MTCY05A6.23 SW:PPGK_MYCTU (Q59568) (265 aa) fasta scores: E(): 1.5e-50, 57.91% id in 240 aa, and to Corynebacterium ammoniagenes polyphosphate glucokinase PpgK TR:Q9AGV8 (EMBL:AF326348) (277 aa) fasta scores: E(): 3.2e-59, 63.85% id in 249 aa.
    
 0.905
glk
Glucose kinase; Similar to Corynebacterium glutamicum glucose kinase Glk TR:Q9KKE7 (EMBL:AF096280) (323 aa) fasta scores: E(): 2.5e-79, 62.38% id in 319 aa, and to Streptomyces coelicolor glucokinase Glk or SC6E10.20c SW:GLK_STRCO (P40184) (317 aa) fasta scores: E(): 5.7e-45, 40% id in 310 aa.
    
 0.905
galT
Similar to Escherichia coli galactose-1-phosphate uridylyltransferase GalT or GalB or B0758 SW:GAL7_ECOLI (P09148) (348 aa) fasta scores: E(): 1.2e-24, 30.34% id in 346 aa, and to Streptomyces lividans galactose-1-phosphate uridylyltransferase GalT SW:GAL7_STRLI (P13212) (354 aa) fasta scores: E(): 4.9e-30, 38.8% id in 384 aa, and to Homo sapiens galactose-1-phosphate uridylyltransferase GalT SW:GAL7_HUMAN (P07902) (379 aa) fasta scores: E(): 8.1e-29, 33.82% id in 340 aa.
 
 
 0.895
DIP1012
Similar to Streptomyces coelicolor putative sodium:solute symporter SCE66.18 TR:Q9K3S5 (EMBL:AL359989) (562 aa) fasta scores: E(): 7e-115, 56.42% id in 553 aa, and to Rattus norvegicus sodium-dependent multivitamin transporter slc5a6 or smvT SW:SL56_RAT (O70247) (634 aa) fasta scores: E(): 3.3e-23, 24.2% id in 504 aa; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
 
     0.793
DIP1013
Putative membrane protein; Similar to Streptomyces coelicolor putative membrane protein SCE66.19 TR:Q9K3S4 (EMBL:AL359989) (98 aa) fasta scores: E(): 6.7e-06, 46.15% id in 65 aa.
 
     0.782
ptsG
Similar to Corynebacterium glutamicum PTS system, glucose-specific IIABC component PtsG SWALL:PTGA_CORGL (SWALL:Q45298) (674 aa) fasta scores: E(): 2.8e-59, 44.91% id in 688 aa, and to Staphylococcus xylosus PTS system, sucrose-specific IIBC component ScrA SWALL:PTSB_STAXY (SWALL:P51184) (480 aa) fasta scores: E(): 8e-26, 27.73% id in 494 aa.
  
  
 0.777
DIP1550
Hypothetical protein; No significant database matches.
  
 
 0.454
DIP2005
Putative D-Ala D-Ala carboxypeptidase; Similar to Mycobacterium tuberculosis hypothetical 46.8 kDa protein Rv3627c or MT3729 or MTCY15C10.25 SWALL:AAK48090 (EMBL:Z95436) (461 aa) fasta scores: E(): 5.2e-11, 37.04% id in 440 aa, and to Escherichia coli penicillin-binding protein 4 precursor DacB or B3182 SWALL:PBP4_ECOLI (SWALL:P24228) (477 aa) fasta scores: E(): 4.4e-05, 26.55% id in 433 aa.
  
    0.409
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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