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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1017Putative NUDIX-family hydrolase; Similar to Staphylococcus aureus (strain N315) SA2278 or SAV2490 TR:BAB58652 (EMBL:AP003137) (130 aa) fasta scores: E(): 1e-24, 56.91% id in 123 aa, and to Escherichia coli CTP pyrophosphohydrolase NudG or B1759 SW:NUDG_ECOLI (P77788) (135 aa) fasta scores: E(): 3.3e-13, 41.4% id in 128 aa. (131 aa)    
Predicted Functional Partners:
DIP1016
Putative helicase; Similar to Streptomyces coelicolor putative helicase SCE20.37 TR:Q9RD88 (EMBL:AL136058) (945 aa) fasta scores: E(): 5.3e-162, 46.4% id in 933 aa, and to Vibrio cholerae helicase-related protein VC0812 TR:Q9KTS6 (EMBL:AE004166) (979 aa) fasta scores: E(): 3.5e-48, 31.6% id in 674 aa.
 
     0.901
DIP2096
Putative RNA methylase family protein; Similar to although shoter in its N-terminal region than Mycobacterium tuberculosis CDC1551 SpoU rRNA methylase family protein MT0393 SWALL:AAK44615 (EMBL:AE006944) (183 aa) fasta scores: E(): 6.2e-51, 74.41% id in 172 aa, and to Escherichia coli tRNA TrmH or SpoU or B3651 or Z5077 or ECS4526 SWALL:TRMH_ECOLI (SWALL:P19396) (229 aa) fasta scores: E(): 4.6e-07, 28.94% id in 152 aa.
 
 
    0.719
deaD
DEAD-box helicase; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.
       0.539
DIP2369
Conserved hypothetical protein; Extensive (but not full length) similarity to Mycobacterium tuberculosis hypothetical 27.1 kDa protein Rv3908 or MTCY15f10.03C TR:O05437 (EMBL:Z94121) (248 aa) fasta scores: E(): 2.3e-25, 47.39% id in 211 aa. Has a hydrophilic N-terminal region; Belongs to the Nudix hydrolase family.
      
 0.454
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.