STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1030Conserved hypothetical protein; Similar to Streptomyces coelicolor hypothetical 23.2 kDa protein SCF43A.07 TR:Q9XAA8 (EMBL:AL096837) (215 aa) fasta scores: E(): 3.3e-26, 44.65% id in 215 aa, and to Deinococcus radiodurans conserved hypothetical protein DR1909 TR:Q9RT57 (EMBL:AE002030) (212 aa) fasta scores: E(): 7.8e-17, 37.44% id in 211 aa. (209 aa)    
Predicted Functional Partners:
DIP1031
Similar to Streptomyces coelicolor putative iron-sulfur protein SCF43A.06 TR:Q9XAA9 (EMBL:AL096837) (492 aa) fasta scores: E(): 9.1e-97, 57.35% id in 483 aa, and to Escherichia coli putative electron transport protein YkgF or B0307 SW:YKGF_ECOLI (P77536) (475 aa) fasta scores: E(): 5.4e-64, 39.41% id in 482 aa.
 
 0.998
DIP1032
Putative oxididoreductase subunit; Similar to C-terminus of e.g. Escherichia coli anaerobic glycerol-3-phosphate dehydrogenase subunit C GlpC or B2243 or Z3501 or ECS3128 SW:GLPC_ECOLI (P13034) (396 aa) fasta scores: E(): 2.8e-11, 27.71% id in 249 aa, and to C-terminus of Escherichia coli glycolate oxidase iron-sulfur subunit GlcF or gox or B2978 SW:GLCF_ECOLI (P52074) (407 aa) fasta scores: E(): 9.8e-10, 23.27% id in 232 aa.
 
 0.987
DIP2133
Putative conserved membrane protein; Similar to many eg. Mycobacterium tuberculosis hypothetical 95.5 kDa protein Rv0338c or MT0352 or MTCY279.05C TR:O33268 (EMBL:Z97991) (882 aa) fasta scores: E(): 2.4e-55, 43.1% id in 877 aa. N-terminal region appears to be has possible membrane-spanning hydrophobic regions while the C-terminal region is rich in proline and alanine.
  
 
 0.700
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
  
  
 0.522
pta
Phosphate acetyltransferase; Highly similar in its C-terminal region to Corynebacterium glutamicum phosphate acetyltransferase Pta SWALL:PTA_CORGL (SWALL:P77844) (329 aa) fasta scores: E(): 6.9e-94, 78.22% id in 326 aa, similar to the C-terminal region of Mycobacterium tuberculosis phosphate acetyltransferase Pta or Rv0408 or MT0421 or MTCY22G10.04 SWALL:PTA_MYCTU (SWALL:P96254) (690 aa) fasta scores: E(): 4.8e-68, 48.67% id in 452 aa, and similar to the C-terminal region of Escherichia coli phosphate acetyltransferase Pta or B2297 SWALL:PTA_ECOLI (SWALL:P39184) (713 aa) fasta scores: [...]
  
  
 0.491
cstA1
Similar to Escherichia coli carbon starvation protein A CstA SW:CSTA_ECOLI (P15078) (701 aa) fasta scores: E(): 2.3e-129, 53.01% id in 696 aa, and to Mycobacterium tuberculosis carbon starvation protein A homologue Rv3063 SW:CSTA_MYCTU (P95095) (758 aa) fasta scores: E(): 5.9e-175, 61.47% id in 719 aa. CDS contains an extended N-terminus in comparison to the E. coli orthologue.
   
  
 0.482
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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