STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
prmCHemK-family methytransferase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. (272 aa)    
Predicted Functional Partners:
prfA
Peptide chain release factor 1 (RF-1); Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
 
 
 0.993
DIP1043
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 22.6 kDa protein Rv1301 or MT1340 or MTCY373.21 SW:YD01_MYCTU (Q10618) (217 aa) fasta scores: E(): 2.3e-50, 64.92% id in 211 aa, and to Bacillus subtilis hypothetical 37.0 kDa protein in spoIIR-glyC intergenic region YwlC or Ipc-29D SW:YWLC_BACSU (P39153) (346 aa) fasta scores: E(): 1.2e-18, 33.01% id in 206 aa; Belongs to the SUA5 family.
 
  
 0.944
rho
Transcription termination factor Rho homolog; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.
       0.836
DIP1044
Glycosyl trasferase; Similar to Mycobacterium tuberculosis putative undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase Rfe or Rv1302 or MT1341 or MTCY373.22 SW:RFE_MYCTU (Q10606) (404 aa) fasta scores: E(): 1e-75, 56.91% id in 369 aa, and to Bacillus subtilis phospho-N-acetylmuramoyl-pentapeptide-transferase MraY SW:MRAY_BACSU (Q03521) (324 aa) fasta scores: E(): 3.6e-10, 26.53% id in 343 aa.
  
    0.663
DIP1045
Hypothetical integral membrane protein; No database matches.
       0.642
atpE
ATP synthase C chain; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
  
   0.564
DIP1038
Similar to Streptomyces coelicolor putative fatty acid CoA ligase 2SC10A7.10 TR:Q9ADP9 (EMBL:AL583945) (558 aa) fasta scores: E(): 1.7e-58, 41.4% id in 570 aa, and to Mycobacterium tuberculosis fatty acid CoA-ligase FadD14 or Rv1058 or MTV017.11 TR:O53406 (EMBL:AL021897) (543 aa) fasta scores: E(): 6.3e-56, 40.59% id in 569 aa, and to Pseudomonas oleovorans medium-chain-fatty-acid--CoA ligase AlkK SW:ALKK_PSEOL (Q00594) (546 aa) fasta scores: E(): 4.5e-47, 34.86% id in 565 aa.
       0.551
atpH
ATP synthase delta chain; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family.
  
   0.523
era
Putative GTP-binding protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
      
 0.511
pth
Putative peptidyl tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
 
    0.470
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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