Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DIP1044Glycosyl trasferase; Similar to Mycobacterium tuberculosis putative undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase Rfe or Rv1302 or MT1341 or MTCY373.22 SW:RFE_MYCTU (Q10606) (404 aa) fasta scores: E(): 1e-75, 56.91% id in 369 aa, and to Bacillus subtilis phospho-N-acetylmuramoyl-pentapeptide-transferase MraY SW:MRAY_BACSU (Q03521) (324 aa) fasta scores: E(): 3.6e-10, 26.53% id in 343 aa. (389 aa)    
Predicted Functional Partners:
DIP0681
Putative glycosyl transferase; Similar to Mycobacterium tuberculosis CDC1551 glycosyl transferase MT3365 TR:AAK47706 (EMBL:AE007146) (301 aa) fasta scores: E(): 5.1e-56, 52.12% id in 282 aa.
 
 
 0.948
bacA
Bacitracin resistance protein; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.
    
 0.910
DIP1043
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 22.6 kDa protein Rv1301 or MT1340 or MTCY373.21 SW:YD01_MYCTU (Q10618) (217 aa) fasta scores: E(): 2.3e-50, 64.92% id in 211 aa, and to Bacillus subtilis hypothetical 37.0 kDa protein in spoIIR-glyC intergenic region YwlC or Ipc-29D SW:YWLC_BACSU (P39153) (346 aa) fasta scores: E(): 1.2e-18, 33.01% id in 206 aa; Belongs to the SUA5 family.
       0.836
DIP1045
Hypothetical integral membrane protein; No database matches.
       0.803
murF
UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
  
 
 0.780
rho
Transcription termination factor Rho homolog; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.
  
    0.665
prfA
Peptide chain release factor 1 (RF-1); Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
       0.663
prmC
HemK-family methytransferase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
  
    0.663
murG
UDP-N-acetylglucosamine-N-acetylmuramyl (pentapeptide); Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.
 
  
 0.660
ftsW
Similar to Mycobacterium tuberculosis probable cell division protein FtsW or Rv0017c or MT0020 or MTCY10H4.17c SW:FTSW_MYCTU (P71587) (469 aa) fasta scores: E(): 8.7e-72, 48.61% id in 434 aa, and to Escherichia coli rod shape-determining protein MrdB or RodA or B0634 or Z0780 or ECS0672 SW:RODA_ECOLI (P15035) (370 aa) fasta scores: E(): 8.5e-19, 26.57% id in 365 aa; Belongs to the SEDS family.
 
  
 0.603
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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