STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1045Hypothetical integral membrane protein; No database matches. (147 aa)    
Predicted Functional Partners:
DIP1043
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 22.6 kDa protein Rv1301 or MT1340 or MTCY373.21 SW:YD01_MYCTU (Q10618) (217 aa) fasta scores: E(): 2.3e-50, 64.92% id in 211 aa, and to Bacillus subtilis hypothetical 37.0 kDa protein in spoIIR-glyC intergenic region YwlC or Ipc-29D SW:YWLC_BACSU (P39153) (346 aa) fasta scores: E(): 1.2e-18, 33.01% id in 206 aa; Belongs to the SUA5 family.
       0.810
DIP1044
Glycosyl trasferase; Similar to Mycobacterium tuberculosis putative undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase Rfe or Rv1302 or MT1341 or MTCY373.22 SW:RFE_MYCTU (Q10606) (404 aa) fasta scores: E(): 1e-75, 56.91% id in 369 aa, and to Bacillus subtilis phospho-N-acetylmuramoyl-pentapeptide-transferase MraY SW:MRAY_BACSU (Q03521) (324 aa) fasta scores: E(): 3.6e-10, 26.53% id in 343 aa.
       0.810
atpB
ATP synthase A chain; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
 
     0.750
DIP2281
Conserved hypothetical protein; Similar to Streptomyces coelicolor hypothetical 44.0 kDa protein SC4G6.31c SWALL:Q9S2S7 (EMBL:AL096884) (403 aa) fasta scores: E(): 4.6e-09, 25.49% id in 459 aa.
  
     0.673
DIP0294
Putative membrane protein; Similar to Deinococcus radiodurans conserved hypothetical protein DR0075 TR:Q9RY75 (EMBL:AE001870) (1467 aa) fasta scores: E(): 3e-06, 27.568% id in 370 aa.
  
     0.666
DIP0605
Hypothetical protein; No significant database matches.
  
     0.666
DIP1673
Conserved hypothetical protein; Low similarity to Streptomyces coelicolor hypothetical 10.4 kDa protein SCC75A.11c TR:Q9RKR3 (EMBL:AL133220) (92 aa) fasta scores: E(): 0.00053, 39.28% id in 56 aa.
  
     0.661
rho
Transcription termination factor Rho homolog; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.
       0.660
prfA
Peptide chain release factor 1 (RF-1); Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
       0.660
prmC
HemK-family methytransferase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
       0.660
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.