STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1060Similar to Streptomyces coelicolor putative iron-siderophore uptake system transmembrane component sci51.26C TR:Q9S214 (EMBL:AL109848) (375 aa) fasta scores: E(): 5e-40, 40.74% id in 324 aa, and to Escherichia coli ferric enterobactin transport system permease protein fepg fepg or B0589 SW:FEPG_ECOLI (P23877) (330 aa) fasta scores: E(): 1.8e-45, 44.09% id in 322 aa; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (319 aa)    
Predicted Functional Partners:
DIP1059
Similar to Streptomyces coelicolor putative iron-siderophore uptake system ATP-binding component SCI51.25C TR:Q9S215 (EMBL:AL109848) (301 aa) fasta scores: E(): 1.9e-42, 50.58% id in 255 aa, and to Escherichia coli ferric enterobactin transport ATP-binding protein fepC b0588 SW:FEPC_ECOLI (P23878) (271 aa) fasta scores: E(): 1.1e-41, 49.61% id in 262 aa.
 
  
 0.973
DIP1061
Similar to Streptomyces coelicolor putative iron-siderophore uptake system transmembrane component sci51.27C TR:Q9S213 (EMBL:AL109848) (348 aa) fasta scores: E(): 8e-36, 36.53% id in 323 aa, and to Escherichia coli ferric enterobactin transport system permease protein fepD or B0590 SW:FEPD_ECOLI (P23876) (334 aa) fasta scores: E(): 5.2e-40, 40.37% id in 322 aa; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
  
0.922
DIP1062
Putative iron-siderophore uptake system exported solute-binding component; Similar to Escherichia coli iron(III) dicitrate-binding periplasmic protein precursor FecB or B4290 SW:FECB_ECOLI (P15028) (300 aa) fasta scores: E(): 1.1e-12, 25.55% id in 270 aa, and to Campylobacter jejuni enterochelin uptake periplasmic binding protein CeuE or CJ1355 TR:Q9PMU4 (EMBL:AL139078) (330 aa) fasta scores: E(): 3e-12, 28.35% id in 328 aa, and to Vibrio anguillarum ferric anguibactin-binding protein precursor FatB SW:FATB_VIBAN (P11460) (322 aa) fasta scores: E(): 1.5e-09, 28.72% id in 289 aa.
 
  
 0.895
ripA
Putative araC-family transcriptional regulator; Under iron limitation, represses the acn (aconitase), catA (catechol 1,2 dioxygenase), leuCD (isopropylmalate dehydratase), narKGHJI (nitrite/nitrate transporter and nitrate reductase), sdhCAB (succinate dehydrogenase), pta (phosphotransacetylase) and katA (catalase) genes.
   
    0.893
DIP0585
Similar to Bacillus subtilis ferrichrome transport ATP-binding protein FhuC SW:FHUC_BACSU (P49938) (269 aa) fasta scores: E(): 1.2e-37, 45.13% id in 257 aa, and to Escherichia coli iron FecE or B4287 SW:FECE_ECOLI (P15031) (255 aa) fasta scores: E(): 5e-32, 42.8% id in 250 aa.
 
  
 0.826
DIP1085
Putative iron ABC transport system, ATP-binding protein; Similar to Bacillus subtilis ferrichrome transport ATP-binding protein FhuC SW:FHUC_BACSU (P49938) (269 aa) fasta scores: E(): 5.1e-24, 35.15% id in 256 aa, and to Escherichia coli iron(III)dicitrate transport ATP-binding protein FecE or B4287 SW:FECE_ECOLI (P15031) (255 aa) fasta scores: E(): 5.5e-24, 37.86% id in 243 aa.
 
  
 0.826
hmuV
Iron-related transport system ATP-binding protein; Almost identical to the previously sequenced Corynebacterium diphtheriae HmuV TR:Q9XD87 (EMBL:AF109162) (277 aa) fasta scores: E(): 3.2e-88, 97.83% id in 277 aa, and to Escherichia coli iron (III) dicitrate transport ATP-binding protein FecE or B4287 SW:FECE_ECOLI (P15031) (255 aa) fasta scores: E(): 1.2e-23, 41.94% id in 236 aa.
  
    0.748
irp6C
ATP-binding protein Irp6C; Almost identical to previously sequenced Corynebacterium diphtheriae ATP-binding protein Irp6C SWALL:Q8VVA6 (EMBL:AY061890) (252 aa) fasta scores: E(): 1.4e-79, 99.6% id in 252 aa and similar to Escherichia coli iron FecE or B4287 SWALL:FECE_ECOLI (SWALL:P15031) (255 aa) fasta scores: E(): 5.7e-19, 37.64% id in 263 aa.
 
  
 0.720
DIP0624
Putative membrane protein; No significant database matches.
   
    0.670
irp6B
Membrane protein permease Irp6B; Almost identical to previously sequenced Corynebacterium diphtheriae membrane protein permease Irp6B SWALL:Q8VVA7 (EMBL:AY061890) (347 aa) fasta scores: E(): 1e-116, 98.27% id in 347 aa and similar to Rhizobium meliloti putative iron ABC transporter permease protein SMB21430 TR:CAC49658 (EMBL:AL603646) (356 aa) fasta scores: E(): 1.6e-55, 50.87% id in 342 aa and to Corynebacterium diphtheriae HmuU SWALL:Q9XD88 (EMBL:AF109162) (350 aa) fasta scores: E(): 2.1e-36, 40.66% id in 332 aa; Belongs to the binding-protein-dependent transport system permease fami [...]
 
  
0.429
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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