STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1072Putative aminotransferase, class V; Similar to Mycobacterium tuberculosis CDC1551 aminotransferase, class V MT3109 TR:AAK47439 (EMBL:AE007129) (393 aa) fasta scores: E(): 1.1e-52, 45.71% id in 385 aa, and to Mycobacterium tuberculosis NifS-like protein Rv3025c or MTV012.40C TR:O53272 (EMBL:AL021287) (393 aa) fasta scores: E(): 1.1e-52, 45.71% id in 385 aa, and to Ruminococcus flavefaciens cysteine desulfurase IscS or NifS SW:ISCS_RUMFL (O54055) (396 aa) fasta scores: E(): 2.1e-40, 36.48% id in 381 aa. (378 aa)    
Predicted Functional Partners:
DIP1291
Similar to Mycobacterium tuberculosis CDC1551 nitrogen fixation protein NifU-related protein MT1512 SWALL:AAK45776 (EMBL:AE007020) (162 aa) fasta scores: E(): 2.6e-35, 63.69% id in 146 aa, and to Bacillus subtilis NifU-like protein NifU SWALL:NIFU_BACSU (SWALL:O32163) (147 aa) fasta scores: E(): 3.7e-18, 44.21% id in 147 aa.
  
 0.998
DIP0034
Similar to Escherichia coli adenylyltransferase ThiF or B3992 SW:THIF_ECOLI (P30138) (251 aa) fasta scores: E(): 1.1e-21, 35.86% id in 237 aa.
 
 
 0.986
DIP0492
Putative molybdopterin biosynthesis protein; Similar to Synechococcus sp MTP-synthase sulfurylase MoeB TR:O54307 (EMBL:Y16560) (391 aa) fasta scores: E(): 1.1e-37, 39.56% id in 369 aa.
   
 0.984
sseA
Similar to Mycobacterium tuberculosis putative thiosulfate sulfurtransferase SseA or Rv3283 or MT3382 or MTCY71.23 SW:THT2_MYCTU (P96888) (297 aa) fasta scores: E(): 1.5e-78, 60.67% id in 295 aa, and to Corynebacterium glutamicum thiosulfate sulfurtransferase ThtR SW:THTR_CORGL (P71121) (225 aa) fasta scores: E(): 1.2e-56, 63.72% id in 215 aa.
   
 0.912
DIP1270
Pseudogene. Similar to Streptomyces coelicolor putative oxidoreductase SCM11.12c SWALL:Q9RIU9 (EMBL:AL133278) (500 aa) fasta scores: E(): 8.9e-41, 52.1% id in 428 aa. Presents multiple frameshifts at residues 33, 93, 121, 293 and 299.
   
 0.912
DIP2099
Putative sulfultransferase; Similar to Streptomyces coelicolor thiosulfate sulfurtransferase SC9B10.21 SWALL:O50528 (EMBL:AL009204) (283 aa) fasta scores: E(): 1.8e-28, 35% id in 280 aa, and to Pseudomonas aeruginosa probable 3-mercaptopyruvate sulfurtransferase SseA or PA1292 SWALL:THTM_PSEAE (SWALL:Q9I452) (284 aa) fasta scores: E(): 2.4e-28, 36.07% id in 280 aa.
   
 0.912
DIP0703
Putative oxidoreductase; Similar to Mycobacterium tuberculosis hypothetical 40.8 kDa protein Rv3230c or MTCY20B11.05c TR:O05875 (EMBL:Z95121) (380 aa) fasta scores: E(): 4.8e-60, 49.14% id in 350 aa, and to Escherichia coli NADH oxidoreductase Hcr or B0872 SW:HCR_ECOLI (P75824) (322 aa) fasta scores: E(): 1.9e-13, 28.71% id in 296 aa.
  
 0.886
DIP0137
Conserved hypothetical protein; Similar to a region of Corynebacterium glutamicum Ycg4K TR:Q9EUM3 (EMBL:AF164956) (256 aa) fasta scores: E(): 9.2e-09, 75.61% id in 41 aa.
  
 0.843
DIP1631
Conserved hypothetical protein; Similar to Corynebacterium glutamicum ORF1 TR:Q9LCB6 (EMBL:AB029550) (114 aa) fasta scores: E(): 3.2e-36, 84.21% id in 114 aa, and to Escherichia coli hypothetical protein YadR or B0156 or Z0167 or ECS0160 SW:YADR_ECOLI (P37026) (114 aa) fasta scores: E(): 7.2e-15, 44.66% id in 103 aa; Belongs to the HesB/IscA family.
 
  
 0.780
DIP2160
Modular polyketide synthase; Similar to Streptomyces verticillus polyketide synthase BlmVIII (bleomycin biosynthesis) TR:Q9FB25 (EMBL:AF210249) (1841 aa) fasta scores: E(): 1.3e-72, 27.240% id in 1931 aa, and to Streptomyces noursei nystatin biosynthesis polyketide synthase Nys TR:Q9L4W3 (EMBL:AF263912) (11096 aa) fasta scores: E(): 4e-71, 33.107% id in 882 aa, and to Amycolatopsis mediterranei rifamycin polyketide synthase TR:Q9F847 (EMBL:AF262754) (1265 aa) fasta scores: E(): 7.7e-61, 31.042% id in 902 aa.
    
 
 0.757
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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