STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1073Putative transferase; Similar to Streptomyces coelicolor hypothetical 30.6 kDa protein 2scc13.11C TR:Q9F3H8 (EMBL:AL442165) (289 aa) fasta scores: E(): 5.6e-28, 36.2% id in 279 aa, and to Neisseria meningitidis (serogroup A), and putative transferase nma1087 or nmb0869 TR:Q9JQL8 (EMBL:AL162755) (263 aa) fasta scores: E(): 1.6e-09, 26.42% id in 246 aa, and to Escherichia coli spermidine synthase spee or B0121 SW:SPEE_ECOLI (P09158) (287 aa) fasta scores: E(): 0.0013, 28.28% id in 152 aa. (282 aa)    
Predicted Functional Partners:
DIP1075
Similar to Mycobacterium leprae hypothetical protein ML1706 TR:Q9CBR6 (EMBL:AL583923) (337 aa) fasta scores: E(): 4.5e-19, 32.26% id in 313 aa, and to Mycobacterium tuberculosis CDC1551 vitamin-b12 independent methionine synthase family protein MT3095 TR:AAK47424 (EMBL:AE007129) (337 aa) fasta scores: E(): 1.4e-18, 31.94% id in 313 aa, and to Mycobacterium tuberculosis hypothetical 34.2 kDa protein Rv3015c or MTV012.29C TR:O53262 (EMBL:AL021287) (337 aa) fasta scores: E(): 1.4e-18, 31.94% id in 313 aa.
 
   
 0.680
trmU
Probable tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
       0.666
pth-2
Putative peptidyl tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
 
     0.423
DIP0906
Putative membrane protein; Low similarity to Streptomyces coelicolor putative integral membrane protein SCI35.39 TR:O88074 (EMBL:AL031541) (394 aa) fasta scores: E(): 1.8e-16, 29.34% id in 351 aa.
 
     0.423
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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