Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DIP1078Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 23.0 kDa protein Rv3013 or MTV012.27 TR:O53260 (EMBL:AL021287) (218 aa) fasta scores: E(): 2.6e-27, 40.63% id in 219 aa, and to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT3093 TR:AAK47422 (EMBL:AE007128) (240 aa) fasta scores: E(): 2.8e-27, 40.63% id in 219 aa, and to Mycobacterium leprae hypothetical 24.4 kDa protein MLCB637.11c TR:O33103 (EMBL:Z99263) (230 aa) fasta scores: E(): 1.3e-26, 40.18% id in 219 aa, and to Mycobacterium leprae hypothetical protein ML1704 TR:Q9CBR7 (EMB [...] (220 aa)    
Predicted Functional Partners:
rpsD
30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
  
 
   0.764
DIP0246
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 17.9 kDa protein Rv3753c or MTV025.10c TR:O69720 (EMBL:AL022121) (166 aa) fasta scores: E(): 1e-20, 45.57% id in 147 aa; Conserved hypothetical protein.
  
     0.761
DIP2295
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 15.0 kDa protein Rv0049 or MT0055 or MTCY21D4.12 SWALL:Y049_MYCTU (SWALL:P71706) (137 aa) fasta scores: E(): 1e-15, 47.52% id in 101 aa.
  
     0.754
DIP1184
Putative secreted protein; Similar to Mycobacterium tuberculosis hypothetical 32.4 kDa protein Rv1698 precursor or MT1737 or MTCI125.20 SWALL:YG98_MYCTU (SWALL:P58212) (314 aa) fasta scores: E(): 4.4e-22, 31.57% id in 304 aa.
  
     0.731
DIP0639
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 45.7 kDa protein Rv3311 or MTV016.10 TR:O53362 (EMBL:AL021841) (420 aa) fasta scores: E(): 1.4e-25, 34.05% id in 417 aa.
  
     0.717
rplB
50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
   
   0.703
rpsE
30S ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family.
   
   0.703
rplT
50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.
   
   0.697
rplX
50S ribosomal protein L24; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
   
   0.696
rplM
50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
  
 
 0.693
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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