STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1081Putative acetyltransferase; Similar to Bacillus halodurans ribosomal-protein (S18)-alanine acetyltransferase BH0547 TR:Q9KFD4 (EMBL:AP001508) (151 aa) fasta scores: E(): 0.0026, 52.83% id in 53 aa, and to Homo sapiens similar to spermidine/spermine N1-acetyl transferase TR:AAH11751 (EMBL:BC011751) (170 aa) fasta scores: E(): 0.0061, 28.85% id in 149 aa. (163 aa)    
Predicted Functional Partners:
DIP1082
Transmembrane efflux protein, major facilitator family; Similar to Mycobacterium tuberculosis CDC1551 drug transporter MT1289 TR:AAK45547 (EMBL:AE007004) (579 aa) fasta scores: E(): 9.3e-70, 43.87% id in 449 aa, and to Streptomyces coelicolor putative transmembrane efflux protein SCD82.12 TR:Q9L0L9 (EMBL:AL160431) (490 aa) fasta scores: E(): 5.7e-43, 31.79% id in 456 aa, and to Streptomyces glaucescens tetracenomycin C resistance and export protein TcmA SW:TCMA_STRGA (P39886) (538 aa) fasta scores: E(): 3.5e-39, 31.29% id in 425 aa; Belongs to the major facilitator superfamily.
       0.572
DIP2066
Some similarity to Actinomyces naeslundii putative fimbrial associated protein TR:O05995 (EMBL:U85708) (375 aa) fasta scores: E(): 0.0012, 28.803% id in 309 aa. Note: Contains a potential sortase anchor site (LPKTG) upstream of the C-terminal region transmembrane domain.
  
    0.454
accBC
Similar to Corynebacterium glutamicum acyl coenzyme A carboxylase AccBC TR:P71122 (EMBL:U35023) (591 aa) fasta scores: E(): 1.5e-188, 85.47% id in 592 aa, and to Mycobacterium leprae acetyl-/propionyl-coenzyme A carboxylase alpha chain [includes: biotin carboxylase (EC 6.3.4.14); biotin carboxyl carrier protein(BCCP)] BccA or ML0726 or B1308_C1_129 SW:BCCA_MYCLE (P46392) (598 aa) fasta scores: E(): 1.1e-159, 72.46% id in 592 aa.
   
   0.415
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.