STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1082Transmembrane efflux protein, major facilitator family; Similar to Mycobacterium tuberculosis CDC1551 drug transporter MT1289 TR:AAK45547 (EMBL:AE007004) (579 aa) fasta scores: E(): 9.3e-70, 43.87% id in 449 aa, and to Streptomyces coelicolor putative transmembrane efflux protein SCD82.12 TR:Q9L0L9 (EMBL:AL160431) (490 aa) fasta scores: E(): 5.7e-43, 31.79% id in 456 aa, and to Streptomyces glaucescens tetracenomycin C resistance and export protein TcmA SW:TCMA_STRGA (P39886) (538 aa) fasta scores: E(): 3.5e-39, 31.29% id in 425 aa; Belongs to the major facilitator superfamily. (471 aa)    
Predicted Functional Partners:
DIP1081
Putative acetyltransferase; Similar to Bacillus halodurans ribosomal-protein (S18)-alanine acetyltransferase BH0547 TR:Q9KFD4 (EMBL:AP001508) (151 aa) fasta scores: E(): 0.0026, 52.83% id in 53 aa, and to Homo sapiens similar to spermidine/spermine N1-acetyl transferase TR:AAH11751 (EMBL:BC011751) (170 aa) fasta scores: E(): 0.0061, 28.85% id in 149 aa.
       0.572
DIP0272
Putative antibiotic resistance protein (membrane protein); Similar to Staphylococcus aureus SA0132 protein TR:Q99X78 (EMBL:AP003129) (450 aa) fasta scores: E(): 3.5e-67, 46.1% id in 436 aa, and to Bacillus subtilis tetracycline resistance protein TetB or Tet SW:TCRB_BACSU (P23054) (458 aa) fasta scores: E(): 1.3e-23, 26.3% id in 403 aa.
  
     0.473
DIP2296
Similar to Mycobacterium tuberculosis CDC1551 transcriptional regulator, MarR family MT0048 SWALL:AAK44270 (EMBL:AE006918) (208 aa) fasta scores: E(): 1.9e-07, 34.72% id in 144 aa, and to Streptomyces coelicolor putative MarR-family transcriptional regulator SC6D11.20 SWALL:Q9L135 (EMBL:AL158061) (155 aa) fasta scores: E(): 4.7e-05, 33.05% id in 121 aa.
 
   
 0.464
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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