STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1086Putative iron transport system exported solute-binding component; Similar to Streptomyces coelicolor putative iron transport lipoprotein SC2H12.17 TR:Q9K467 (EMBL:AL359215) (345 aa) fasta scores: E(): 8.3e-30, 36.76% id in 321 aa, and to Yersinia pestis hemin-binding periplasmic protein HmuT precursor YPO0281 SW:HMUT_YERPE (Q56991) (279 aa) fasta scores: E(): 0.022, 22.69% id in 282 aa. (354 aa)    
Predicted Functional Partners:
DIP1084
Similar to Streptomyces coelicolor putative FecCD-family membrane transport protein SC2H12.15 TR:Q9K469 (EMBL:AL359215) (368 aa) fasta scores: E(): 2.3e-50, 48.1% id in 343 aa, and to Yersinia pestis hemin transport system permease protein HmuU YPO0280 SW:HMUU_YERPE (Q56992) (334 aa) fasta scores: E(): 6.8e-30, 36.33% id in 344 aa.
 
 
 0.942
DIP1085
Putative iron ABC transport system, ATP-binding protein; Similar to Bacillus subtilis ferrichrome transport ATP-binding protein FhuC SW:FHUC_BACSU (P49938) (269 aa) fasta scores: E(): 5.1e-24, 35.15% id in 256 aa, and to Escherichia coli iron(III)dicitrate transport ATP-binding protein FecE or B4287 SW:FECE_ECOLI (P15031) (255 aa) fasta scores: E(): 5.5e-24, 37.86% id in 243 aa.
 
 
 0.926
DIP0585
Similar to Bacillus subtilis ferrichrome transport ATP-binding protein FhuC SW:FHUC_BACSU (P49938) (269 aa) fasta scores: E(): 1.2e-37, 45.13% id in 257 aa, and to Escherichia coli iron FecE or B4287 SW:FECE_ECOLI (P15031) (255 aa) fasta scores: E(): 5e-32, 42.8% id in 250 aa.
  
 
 0.720
irp6B
Membrane protein permease Irp6B; Almost identical to previously sequenced Corynebacterium diphtheriae membrane protein permease Irp6B SWALL:Q8VVA7 (EMBL:AY061890) (347 aa) fasta scores: E(): 1e-116, 98.27% id in 347 aa and similar to Rhizobium meliloti putative iron ABC transporter permease protein SMB21430 TR:CAC49658 (EMBL:AL603646) (356 aa) fasta scores: E(): 1.6e-55, 50.87% id in 342 aa and to Corynebacterium diphtheriae HmuU SWALL:Q9XD88 (EMBL:AF109162) (350 aa) fasta scores: E(): 2.1e-36, 40.66% id in 332 aa; Belongs to the binding-protein-dependent transport system permease fami [...]
 
 
 0.643
hmuU
Iron-related transport system membrane protein; Almost identical to previously sequenced Corynebacterium diphtheriae HmuU TR:Q9XD88 (EMBL:AF109162) (350 aa) fasta scores: E(): 6.1e-120, 98% id in 350 aa, and highly similar to Corynebacterium ulcerans permease HmuU TR:Q9EZ56 (EMBL:AF304009) (350 aa) fasta scores: E(): 4.3e-100, 81.14% id in 350 aa; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
 
 0.638
DIP0584
Putative iron transport system membrane protein; Similar to Escherichia coli iron FecD or B4288 SW:FECD_ECOLI (P15029) (318 aa) fasta scores: E(): 2.6e-28, 35.01% id in 317 aa; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
  
 
 0.582
irp6C
ATP-binding protein Irp6C; Almost identical to previously sequenced Corynebacterium diphtheriae ATP-binding protein Irp6C SWALL:Q8VVA6 (EMBL:AY061890) (252 aa) fasta scores: E(): 1.4e-79, 99.6% id in 252 aa and similar to Escherichia coli iron FecE or B4287 SWALL:FECE_ECOLI (SWALL:P15031) (255 aa) fasta scores: E(): 5.7e-19, 37.64% id in 263 aa.
  
 
 0.580
DIP1059
Similar to Streptomyces coelicolor putative iron-siderophore uptake system ATP-binding component SCI51.25C TR:Q9S215 (EMBL:AL109848) (301 aa) fasta scores: E(): 1.9e-42, 50.58% id in 255 aa, and to Escherichia coli ferric enterobactin transport ATP-binding protein fepC b0588 SW:FEPC_ECOLI (P23878) (271 aa) fasta scores: E(): 1.1e-41, 49.61% id in 262 aa.
  
 
 0.580
DIP2206
Putative nucleotide-binding protein; No significant database matches.
  
 
 0.580
DIP0583
Putative iron transport system membrane protein; Similar to Escherichia coli iron FecC or B4289 SW:FECC_ECOLI (P15030) (332 aa) fasta scores: E(): 1.6e-22, 33.77% id in 305 aa; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
  
   0.573
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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