Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
DIP1090Putative aldo/keto-reductase family protein; Similar to Escherichia coli ORF_O346 B3001 TR:Q46851 (EMBL:U28377) (346 aa) fasta scores: E(): 2.5e-73, 56.21% id in 354 aa, to Streptomyces coelicolor putative oxidoreductase SC7H9.06 TR:Q9EWJ0 (EMBL:AL450223) (348 aa) fasta scores: E(): 1.6e-65, 58.48% id in 342 aa, and to Homo sapiens voltage-gated potassium channel beta-2 subunit KcnAB2 or KcnA2B or KcnK2 TR:Q13303 (EMBL:U33429) (367 aa) fasta scores: E(): 9.5e-27, 34.74% id in 331 aa. (365 aa)    
Predicted Functional Partners:
glpF
Similar to Bacillus subtilis glycerol uptake facilitator protein GlpF SW:GLPF_BACSU (P18156) (274 aa) fasta scores: E(): 2.1e-23, 45.83% id in 240 aa; Belongs to the MIP/aquaporin (TC 1.A.8) family.
    
 
 0.709
gatB
glutamyl-tRNA(Gln) amidotransferase subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily.
  
    0.666
DIP0788
Similar to Streptomyces coelicolor putative oxidoreductase SC4B5.01c TR:Q9ZBW7 (EMBL:AL034443) (277 aa) fasta scores: E(): 1.3e-48, 48% id in 275 aa, and to Corynebacterium sp 2,5-diketo-D-gluconic acid reductase SW:2DKG_CORSP (P15339) (277 aa) fasta scores: E(): 1.1e-39, 44.52% id in 274 aa.
  
 
 0.465
DIP1638
Putative oxidoreductase; Similar to Saccharopolyspora erythraea ORF1, 5' end; NADH-ferredoxin oxidoreductase (fragment) TR:Q54100 (EMBL:L38646) (93 aa) fasta scores: E(): 1.9e-08, 42.16% id in 83 aa.
    
   0.461
DIP1768
Conserved hypothetical protein; Similar to Streptomyces coelicolor putative ankyrin-like protein SC6D7.25 TR:Q9RKX3 (EMBL:AL133213) (134 aa) fasta scores: E(): 4.4e-23, 57.36% id in 129 aa, and to Campylobacter jejuni ankyrin-repeat containing protein Cj1386 TR:Q9PMR4 (EMBL:AL139078) (156 aa) fasta scores: E(): 1.2e-10, 39.66% id in 121 aa.
    
 
 0.450
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
  0.430
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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