Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
lysELysine exporter protein; Catalyzes the efflux of L-lysine. Belongs to the LysE/ArgO transporter (TC 2.A.75) family. (228 aa)    
Predicted Functional Partners:
lysG
Similar to Corynebacterium glutamicum lysine export transcriptional regulatory protein LysG SW:LYSG_CORGL (P94632) (290 aa) fasta scores: E(): 3.2e-70, 62.54% id in 291 aa, and to Streptomyces coelicolor putative LysR-family transcriptional regulator SC5F8.17c TR:Q9K4K7 (EMBL:AL357613) (300 aa) fasta scores: E(): 3.8e-43, 46.8% id in 297 aa, and to Rhodococcus fascians AttR protein TR:CAC43333 (EMBL:AJ311775) (320 aa) fasta scores: E(): 2.2e-37, 43.43% id in 297 aa.
 
   
 0.990
DIP1767
Putative LysE type translocator; Similar to Escherichia coli threonine efflux protein RhtC SW:RHTC_ECOLI (P27846) (206 aa) fasta scores: E(): 2.7e-18, 30.43% id in 207 aa, and to Salmonella typhimurium LT2 putative threonine efflux protein RhtC TR:Q9L6N7 (EMBL:AF233324) (206 aa) fasta scores: E(): 1.7e-18, 30.88% id in 204 aa.
  
   
 0.538
DIP2129
Putative binding-protein-dependent integral membrane transport protein; Similar to Mycobacterium tuberculosis putative phosphate permease Rv2281 or MT2339 or MTCY339.29C SW:YM81_MYCTU (Q50684) (552 aa) fasta scores: E(): 1.2e-121, 61% id in 518 aa.
      
 0.529
hemA
Putative glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
      
 0.495
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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