close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lysGSimilar to Corynebacterium glutamicum lysine export transcriptional regulatory protein LysG SW:LYSG_CORGL (P94632) (290 aa) fasta scores: E(): 3.2e-70, 62.54% id in 291 aa, and to Streptomyces coelicolor putative LysR-family transcriptional regulator SC5F8.17c TR:Q9K4K7 (EMBL:AL357613) (300 aa) fasta scores: E(): 3.8e-43, 46.8% id in 297 aa, and to Rhodococcus fascians AttR protein TR:CAC43333 (EMBL:AJ311775) (320 aa) fasta scores: E(): 2.2e-37, 43.43% id in 297 aa. (293 aa)    
Predicted Functional Partners:
lysE
Lysine exporter protein; Catalyzes the efflux of L-lysine. Belongs to the LysE/ArgO transporter (TC 2.A.75) family.
 
   
 0.971
DIP2250
Putative membrane protein; Region similar to many eg. Streptomyces coelicolor putative membrane protein SCBAC19G2.03c TR:CAC44513 (EMBL:AL596138) (397 aa) fasta scores: E(): 4.6e-19, 36.91% id in 409 aa, and to Staphylococcus aureus (strain N315), and SA2103 protein or SAV2310 TR:BAB58472 (EMBL:AP003136) (315 aa) fasta scores: E(): 4.5e-13, 31.07% id in 280 aa.
   
    0.713
DIP1296
Putative DNA-binding protein; Similar to Mycobacterium tuberculosis hypothetical 29.2 kDa protein Rv1460 or MTV007.07 SWALL:O53151 (EMBL:AL021184) (278 aa) fasta scores: E(): 3.4e-38, 46.25% id in 240 aa, and to Streptomyces coelicolor putative DNA-binding protein scc22.08C SWALL:Q9XAD0 (EMBL:AL096839) (252 aa) fasta scores: E(): 9e-27, 42.35% id in 229 aa.
   
    0.672
DIP0619
Putative diphtheria toxin repressor 2; Similar to Mycobacterium tuberculosis iron-dependent repressor IdeR or DtxR or Rv2711 or MT2784 or MTCY05A6.32 SW:IDER_MYCTU (Q50495) (230 aa) fasta scores: E(): 1.1e-10, 31.84% id in 201 aa and low similarity to Corynebacterium diphtheriae diphtheria toxin repressor DtxR SW:DTXR_CORDI (P33120) (226 aa) fasta scores: E(): 7.7e-08, 35.08% identity in 114 aa overlap.
   
 
 0.600
DIP1844
Putative TetR-family regulatory protein; Similar to Rhizobium loti transcriptional regulator MLL3939 TR:Q98F48 (EMBL:AP003003) (209 aa) fasta scores: E(): 4.6e-12, 33.65% id in 208 aa, and to Pseudomonas aeruginosa probable transcriptional regulator PA1403 TR:Q9I3U1 (EMBL:AE004569) (210 aa) fasta scores: E(): 2e-05, 27.57% id in 214 aa.
   
   0.519
DIP2241
Similar to Streptomyces coelicolor putative GntR-family transcriptional regulator SC7E4.28c TR:Q9K492 (EMBL:AL359214) (254 aa) fasta scores: E(): 7.3e-21, 34.82% id in 224 aa, and to Escherichia coli fatty acyl responsive regulator FarR or G30 or B0730 SW:FARR_ECOLI (P13669) (240 aa) fasta scores: E(): 6.4e-14, 30.93% id in 236 aa.
   
  
 0.517
DIP0905
Putative LysR family transcriptional regulator; Similar to Pseudomonas aeruginosa probable transcriptional regulator PA3398 TR:Q9HYK6 (EMBL:AE004761) (308 aa) fasta scores: E(): 4e-18, 30.94% id in 265 aa; Belongs to the LysR transcriptional regulatory family.
   
    0.508
DIP0011
Putative regulatory protein; Similar to Escherichia coli glc operon transcriptional activator GlcC or B2980 SW:GLCC_ECOLI (P52072) (254 aa) fasta scores: E(): 1.2e-05, 23.5% id in 234 aa.
  
  
 0.494
DIP0494
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis CDC1551 hypothetical 24.2 kDa protein MT2696 TR:AAK47012 (EMBL:AE007102) (224 aa) fasta scores: E(): 1.3e-10, 31.37% id in 204 aa.
   
    0.429
DIP1879
Putative DNA-biding protein; Similar to Mycobacterium tuberculosis hypothetical protein Rv2621c TR:O06191 (EMBL:Z95387) (224 aa) fasta scores: E(): 2.3e-05, 27.12% id in 188 aa, and to Deinococcus radiodurans conserved hypothetical protein DR0999 TR:Q9RvM8 (EMBL:AE001952) (225 aa) fasta scores: E(): 0.01, 23.62% id in 182 aa.
   
    0.429
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.