STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1093Conserved hypothetical protein; Similar to Streptomyces lividans and S. coelicolor hypothetical 38.1 kDa protein 3SCF60.09 TR:O85700 (EMBL:AF072709) (341 aa) fasta scores: E(): 4.8e-70, 54.38% id in 331 aa, and to Rhodobacter sphaeroides hypothetical 38.5 kDa protein ORF11 TR:O33560 (EMBL:AJ000977) (333 aa) fasta scores: E(): 5.6e-48, 45.28% id in 318 aa. (360 aa)    
Predicted Functional Partners:
DIP1094
Similar to Mycobacterium tuberculosis hypothetical 25.9 kDa protein Rv2972c or MTCY349.15 TR:P95123 (EMBL:Z83018) (237 aa) fasta scores: E(): 3.4e-25, 36.55% id in 238 aa, and to Streptomyces coelicolor putative lipoprotein SCE41.16c TR:Q9F2P3 (EMBL:AL442120) (258 aa) fasta scores: E(): 1.5e-19, 37.86% id in 169 aa. Note: Contains a putative twin-arginine translocation (TAT) system recognition motif (RRSFIRK) at the N-terminal region.
       0.700
DIP1095
Conserved hypothetical integral membrane protein; Similar to Mycobacterium leprae hypothetical 29.5 kDa protein ML1698 or MLCB637.18 TR:O33110 (EMBL:Z99263) (277 aa) fasta scores: E(): 6.4e-10, 30.79% id in 276 aa, and to Mycobacterium tuberculosis hypothetical 28.9 kDa protein Rv3005c or MTV012.19c TR:O53252 (EMBL:AL021287) (279 aa) fasta scores: E(): 1.3e-08, 28.15% id in 277 aa.
  
    0.616
DIP1389
Putative secreted protein; Similar to Yersinia pestis hypothetical protein YPO1856 SWALL:Q8ZF62 (EMBL:AJ414150) (434 aa) fasta scores: E(): 8.7e-30, 33.74% id in 406 aa, and to Escherichia coli hypothetical protein YcdB precursor or B1019 SWALL:YCDB_ECOLI (SWALL:P31545) (423 aa) fasta scores: E(): 2.4e-29, 32.22% id in 419 aa. Note: Contains a putative twin-arginine translocation (TAT) system recognition motif (RRGFLT) at the N-terminal region.
      
 0.477
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
Server load: low (38%) [HD]