STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1110Conserved hypothetical protein (pseudogene); ProfileScan hit to PS50147, SNF4 repeat. (59 aa)    
Predicted Functional Partners:
DIP1111
Putative integral membrane protein; No significant database matches.
       0.625
DIP1112
Putative hydrolase, FAA-family; Similar to Mycobacterium tuberculosis possible 2-hydroxyhepta-2,4-diene- 1,7-dioate isomerase Rv2993c or MTV012.07c TR:O53242 (EMBL:AL021287) (239 aa) fasta scores: E(): 2.5e-42, 48.73% id in 238 aa.
       0.472
DIP1113
Conserved hypothetical protein; Similar to Streptomyces coelicolor putative methyltransferase SCF43A.25c TR:Q9XA90 (EMBL:AL096837) (215 aa) fasta scores: E(): 2.2e-12, 36.23% id in 207 aa.
  
    0.435
dnaN
DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...]
   
 
 0.415
dnaX
DNA polymerase III subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
    
 
 0.401
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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