STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1112Putative hydrolase, FAA-family; Similar to Mycobacterium tuberculosis possible 2-hydroxyhepta-2,4-diene- 1,7-dioate isomerase Rv2993c or MTV012.07c TR:O53242 (EMBL:AL021287) (239 aa) fasta scores: E(): 2.5e-42, 48.73% id in 238 aa. (265 aa)    
Predicted Functional Partners:
DIP1113
Conserved hypothetical protein; Similar to Streptomyces coelicolor putative methyltransferase SCF43A.25c TR:Q9XA90 (EMBL:AL096837) (215 aa) fasta scores: E(): 2.2e-12, 36.23% id in 207 aa.
       0.796
DIP1111
Putative integral membrane protein; No significant database matches.
       0.565
DIP1110
Conserved hypothetical protein (pseudogene); ProfileScan hit to PS50147, SNF4 repeat.
       0.472
serA
Similar to Mycobacterium tuberculosis D-3-phosphoglycerate dehydrogenase SerA or Rv2996c or MT3074 or MTV012.10 SW:SERA_MYCTU (O53243) (528 aa) fasta scores: E(): 3.6e-129, 67.56% id in 521 aa, and to Homo sapiens D-3-phosphoglycerate dehydrogenase PhgDH SW:SERA_HUMAN (O43175) (533 aa) fasta scores: E(): 1.4e-43, 34.47% id in 438 aa; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
 
   
 0.468
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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