STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1118Integral membrane protein, MmpL family; Similar to Streptomyces coelicolor putative membrane protein SC10A5.10c SW:MMLB_STRCO (O54101) (847 aa) fasta scores: E(): 5.3e-106, 47.61% id in 733 aa, and to Mycobacterium tuberculosis putative membrane protein MmpL8 or Rv3823c or MT3931 or MTCY409.07 SW:MML8_MYCTU (O07800) (1089 aa) fasta scores: E(): 1.1e-21, 27.76% id in 461 aa. (717 aa)    
Predicted Functional Partners:
DIP0789
Putative hydratase; Similar to Mycobacterium leprae probable enoyl-CoA hydratase EchA6 or ML2118 or U650AF SW:ECH6_MYCLE (Q50130) (247 aa) fasta scores: E(): 3.6e-24, 38.86% id in 247 aa, and to Escherichia coli probable enoyl-CoA hydratase PaaF or B1393 SW:PAAF_ECOLI (P76082) (255 aa) fasta scores: E(): 3.3e-13, 34.25% id in 254 aa; Belongs to the enoyl-CoA hydratase/isomerase family.
      
 0.618
DIP1117
Putative TetR-family transcriptional regulator; Similar to Streptomyces coelicolor SC10A5.11 protein TR:O54102 (EMBL:AL021529) (198 aa) fasta scores: E(): 8.8e-14, 32.94% id in 170 aa, and to Streptomyces roseosporus WhiR protein TR:P72569 (EMBL:U58281) (179 aa) fasta scores: E(): 1.5e-05, 24.5% id in 151 aa.
       0.535
accDA
Similar to Corynebacterium glutamicum putative carboxyltransferase subunit of acetyl-CoA carboxylase AccDA TR:CAC42827 (EMBL:Y17592) (491 aa) fasta scores: E(): 8.9e-58, 55.31% id in 499 aa, and to Escherichia coli acetyl-coenzyme A carboxylase carboxyl transferase subunit beta AccD or DedB or Usg or B2316 or Z3578 or ECS3200 SW:ACCD_ECOLI (P08193) (304 aa) fasta scores: E(): 8.6e-22, 34.89% id in 235 aa.
     
 0.525
DIP2189
Putative polyketide synthase; Similar to Mycobacterium tuberculosis polyketide synthase PKS13 or Rv3800c or MTV026.05c TR:O53579 (EMBL:AL022076) (1733 aa) fasta scores: E(): 5.4e-109, 44.5% id in 1719 aa, and to Polyangium cellulosum soraphen polyketide synthase A SorA TR:Q9ADL6 (EMBL:U24241) (6315 aa) fasta scores: E(): 6.2e-101, 35.96% id in 1090 aa.
    
 
 0.524
DIP2160
Modular polyketide synthase; Similar to Streptomyces verticillus polyketide synthase BlmVIII (bleomycin biosynthesis) TR:Q9FB25 (EMBL:AF210249) (1841 aa) fasta scores: E(): 1.3e-72, 27.240% id in 1931 aa, and to Streptomyces noursei nystatin biosynthesis polyketide synthase Nys TR:Q9L4W3 (EMBL:AF263912) (11096 aa) fasta scores: E(): 4e-71, 33.107% id in 882 aa, and to Amycolatopsis mediterranei rifamycin polyketide synthase TR:Q9F847 (EMBL:AF262754) (1265 aa) fasta scores: E(): 7.7e-61, 31.042% id in 902 aa.
   
 
 0.510
DIP1119
Similar to Mycobacterium leprae hypothetical protein ML0099 TR:Q9CDB3 (EMBL:AL583917) (336 aa) fasta scores: E(): 7e-07, 27.58% id in 261 aa, and to Mycobacterium tuberculosis hypothetical 35.4 kDa protein Rv3802c or MTV026.07c TR:O53581 (EMBL:AL022076) (336 aa) fasta scores: E(): 4.2e-06, 27.98% id in 243 aa.
       0.458
DIP1871
Similar to Neurospora crassa phytoene dehydrogenase Al-1 SW:CRTI_NEUCR (P21334) (595 aa) fasta scores: E(): 1.6e-33, 29.77% id in 524 aa, and to Corynebacterium glutamicum phytoene desaturase CrtI TR:AAK64299 (EMBL:AF159510) (549 aa) fasta scores: E(): 5.6e-107, 54.59% id in 511 aa.
     
 0.455
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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