STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1125Similar to Synechocystis sp. hypothetical 21.9 kDa protein SLL1660 SWALL:P72810 (EMBL:D90901) (194 aa) fasta scores: E(): 2.9e-16, 33.13% id in 166 aa, and to Pseudomonas denitrificans hypothetical 19.2 kDa protein in cobO 3'region SWALL:YCB8_PSEDE (SWALL:P29941) (175 aa) fasta scores: E(): 6.6e-07, 34.24% id in 146 aa. (185 aa)    
Predicted Functional Partners:
rplX
50S ribosomal protein L24; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
  
   0.765
rpsR2
30S ribosomal protein S18-2; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.
  
 
   0.757
rpmB2
Similar to Mycobacterium tuberculosis 50S ribosomal protein L28-2 RpmB2 or Rv2058c or MT2118 or MTCY63A.02 SW:R28B_MYCTU (O86357) (78 aa) fasta scores: E(): 7.7e-22, 70.51% id in 78 aa; Belongs to the bacterial ribosomal protein bL28 family.
 
   0.751
rplK
50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
    
 
 0.731
rplM
50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
  
 
 0.727
rplB
50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
   
   0.725
rpsE
30S ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family.
   
   0.725
rpsL
30S ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy.
    
 
 0.723
rpmI
Similar to Streptomyces coelicolor 50S ribosomal protein L35 RpmI or SCI35.21c SWALL:RL35_STRCO (SWALL:O88059) (64 aa) fasta scores: E(): 1.1e-10, 58.06% id in 62 aa, and to Bacillus subtilis 50S ribosomal protein L35 RpmI SWALL:RL35_BACSU (SWALL:P55874) (65 aa) fasta scores: E(): 1.5e-07, 50% id in 60 aa; Belongs to the bacterial ribosomal protein bL35 family.
   
 
 0.723
rplT
50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.
   
   0.719
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.