STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1126Similar to Mycobacterium tuberculosis probable transcriptional regulator Rv2989 or MT3067 or MTV012.03 SWALL:AAK47396 (EMBL:AL021287) (267 aa) fasta scores: E(): 8.6e-39, 48.26% id in 230 aa, and to Streptomyces coelicolor putative transcriptional regulator SC1C2.33c SWALL:O86533 (EMBL:AL031124) (238 aa) fasta scores: E(): 7.2e-31, 42.24% id in 232 aa. (241 aa)    
Predicted Functional Partners:
leuC
3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
  
  
 0.944
leuD
3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
  
    0.896
DIP2081
Similar to Escherichia coli O157:H7 transcriptional regulator LldR or Z5031 or ECS4482 SWALL:BAB37905 (EMBL:AE005588) (258 aa) fasta scores: E(): 1.9e-14, 33.48% id in 224 aa, and to Pseudomonas aeruginosa transcriptional regulator GlcC or PA5356 SWALL:Q9HTK2 (EMBL:AE004947) (251 aa) fasta scores: E(): 1e-13, 32.36% id in 241 aa.
  
  
 0.595
DIP0517
Putative GntR family regulatory protein; Similar to Escherichia coli galactonate operon transcriptional repressor DgoR or B3694/B3695 SW:DGOR_ECOLI (P31460) (229 aa) fasta scores: E(): 8.4e-09, 23.11% id in 199 aa.
  
  
 0.534
DIP1686
Conserved hypothetical protein; Similar to Mycobacterium leprae hypothetical 15.2 kDa protein ML1649 or MLCB1243.26 TR:O69479 (EMBL:AL023635) (140 aa) fasta scores: E(): 4.1e-24, 56.55% id in 122 aa.
  
     0.455
DIP1004
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 27.6 kDa protein Rv1249c or MTV006.21c TR:O50464 (EMBL:AL021006) (262 aa) fasta scores: E(): 2.1e-15, 31.57% id in 209 aa.
  
    0.414
DIP0011
Putative regulatory protein; Similar to Escherichia coli glc operon transcriptional activator GlcC or B2980 SW:GLCC_ECOLI (P52072) (254 aa) fasta scores: E(): 1.2e-05, 23.5% id in 234 aa.
  
  
 0.405
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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