STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gpsASimilar to Mycobacterium tuberculosis glycerol-3-phosphate dehydrogenase GpsA or GpdA2 or Rv2982c or MT3060 or MTCY349.05 SWALL:GPDA_MYCTU (SWALL:P95113) (334 aa) fasta scores: E(): 8.7e-69, 59.27% id in 329 aa, and to Bacillus subtilis glycerol-3-phosphate dehydrogenase GpsA or GlyC SWALL:GPDA_BACSU (SWALL:P46919) (345 aa) fasta scores: E(): 2.1e-43, 40.78% id in 331 aa; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (331 aa)    
Predicted Functional Partners:
glpD
Similar to Mycobacterium leprae glycerol-3-phosphate dehydrogenase GlpD or ML0713 or L308_C1_179 SW:GLPD_MYCLE (P53435) (585 aa) fasta scores: E(): 5.7e-116, 55.35% id in 560 aa, and to Escherichia coli aerobic glycerol-3-phosphate dehydrogenase GlpD or GlyD or B3426 SW:GLPD_ECOLI (P13035) (501 aa) fasta scores: E(): 2.4e-38, 33.67% id in 493 aa.
   
 0.930
DIP1618
Putative acyltransferase; Similar to Corynebacterium glutamicum hypothetical 27.1 kDa protein TR:Q9KKE6 (EMBL:AF096280) (245 aa) fasta scores: E(): 1.9e-67, 67.91% id in 240 aa, and to Streptomyces coelicolor putative acyltransferase 2SCG1.03 TR:Q9FCD9 (EMBL:AL391014) (240 aa) fasta scores: E(): 1.3e-37, 46.63% id in 238 aa.
  
 0.929
engA
Putative GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
 
  
 0.925
fas
Putative fatty acid synthase; Similar to the N-terminal region of Corynebacterium ammoniagenes fatty acid synthase Fas TR:Q04846 (EMBL:X64795) (3104 aa) fasta scores: E(): 0, 61.33% id in 3018 aa, and to the full length of Mycobacterium tuberculosis fatty acid synthase Rv2524c TR:AAK46907 (EMBL:Z83863) (3069 aa) fasta scores: E(): 1e-197, 51.37% id in 3083 aa, and of Corynebacterium glutamicum 3-oxoacyl-(acyl-carrier-protein) synthase CGL2495 SWALL:Q8NMS0 (EMBL:AP005281) (2993 aa) fasta scores: E(): 0, 67.35% id in 3008 aa.
  
  
 0.891
ddl
D-alanine--d-alanine ligase; Cell wall formation.
     
 0.841
DIP2336
Similar to but longer than a family of hypothetical proteins eg. Deinococcus radiodurans conserved hypothetical protein DRB0052 SWALL:Q9RZR3 (EMBL:AE001826) (133 aa) fasta scores: E(): 8.8e-10, 43.75% id in 128 aa, and to Staphylococcus aureus (strain N315) hypothetical protein SA0607 or SAV0652 SWALL:Q99VW9 (EMBL:AP003131) (120 aa) fasta scores: E(): 1.3e-09, 42.73% id in 117 aa.
   
 
  0.812
DIP2334
Putative dihydroxyacetone kinase sununit; Similar to Streptomyces coelicolor hypothetical 34.3 kDa protein SC4G1.39c SWALL:Q9FC11 (EMBL:AL391039) (330 aa) fasta scores: E(): 3e-61, 56.62% id in 332 aa, and to Selenomonas ruminantium subspruminantium dihydroxyacetone kinase Dhak1 SWALL:AAK84068 (EMBL:AF297121) (329 aa) fasta scores: E(): 7.8e-61, 56.19% id in 331 aa, and to Lycopersicon esculentum putative 3,4-dihydroxy-2-butanone kinase DhbK SWALL:DHBK_LYCES (SWALL:O04059) (594 aa) fasta scores: E(): 2.6e-42, 45.64% id in 333 aa. Lies upstream of a Dhak2 homologue.
   
 
 0.808
DIP2335
Similar to Selenomonas ruminantium subspruminantium dihydroxyacetone kinase Dhak2 SWALL:AAG14892 (EMBL:AF297121) (207 aa) fasta scores: E(): 6.6e-25, 48.51% id in 202 aa, and to Escherichia coli protein YcgS or B1199 SWALL:YCGS_ECOLI (SWALL:P76014) (210 aa) fasta scores: E(): 2e-22, 43.12% id in 211 aa. Lies downstream of a Dhak1 homologue.
   
 
 0.808
DIP1129
Similar to Mycobacterium leprae hypothetical protein ML1682 SWALL:Q9CBR8 (EMBL:AL583923) (311 aa) fasta scores: E(): 1.4e-40, 42.66% id in 300 aa, and N-terminal region to Streptomyces coelicolor putative MutT-like protein SCD84.10c SWALL:Q9KZV8 (EMBL:AL353816) (142 aa) fasta scores: E(): 4.4e-13, 42.4% id in 125 aa.
  
  
 0.686
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
   
 
 0.615
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
Server load: medium (54%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.