STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
coaDPhosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (159 aa)    
Predicted Functional Partners:
dfp
DNA/pantothenate metabolism flavoprotein homolog; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.
 
  
 0.983
DIP1138
Putative DNA methylase; Similar to Mycobacterium tuberculosis hypothetical 19.8 kDa protein Rv2966c or MTCY349.21 TR:P95128 (EMBL:Z83018) (188 aa) fasta scores: E(): 2.6e-22, 42.703% id in 185 aa, and to Streptomyces coelicolor putative methylase SC7A1.11 TR:Q9ZBR2 (EMBL:AL034447) (195 aa) fasta scores: E(): 1.2e-21, 44.505% id in 182 aa.
 
  
 0.973
coaE
dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
    
 0.960
coaA
Pantothenate kinase; Similar to Escherichia coli pantothenate kinase CoaA or Rts or PanK or B3974 or Z5545 or ECS4901 SW:COAA_ECOLI (P15044) (316 aa) fasta scores: E(): 7.4e-62, 52.27% id in 308 aa, and to Mycobacterium tuberculosis pantothenate kinase CoaA or Rv1092c or MT1124 or MTV017.45C SW:COAA_MYCTU (O53440) (312 aa) fasta scores: E(): 1e-76, 64.42% id in 312 aa.
     
 0.957
DIP1137
Putative biotin carboxyl carrier protein; Similar to C-terminus of Mycobacterium smegmatis pyruvate carboxylase Pyc TR:Q9F843 (EMBL:AF262949) (1127 aa) fasta scores: E(): 1.9e-05, 47.761% id in 67 aa, to Bacillus subtilis YngXX TR:Q9R9I3 (EMBL:AF184956) (73 aa) fasta scores: E(): 0.0043, 36.765% id in 68 aa, and to Propionibacterium freudenreichii shermanii biotin carboxyl carrier protein of methylmalonyl-CoA carboxyl- transferase SW:BCCP_PROFR (P02904) (123 aa) fasta scores: E(): 0.0079, 38.806% id in 67 aa.
  
    0.844
DIP1135
Putative kinase; Similar to Mycobacterium tuberculosis hypothetical 46.7 kDa protein Rv2974c or MTCY349.13 TR:P95121 (EMBL:Z83018) (470 aa) fasta scores: E(): 4e-28, 33.402% id in 485 aa, and to Clostridium acetobutylicum predicted kinase related to hydroxyacetone kinase YloV ortholog CAC1735 TR:AAK79701 (EMBL:AE007682) (547 aa) fasta scores: E(): 3.8e-21, 25.690% id in 471 aa.
 
     0.820
recG
Similar to Bacillus subtilis ATP-dependent DNA helicase RecG SW:RECG_BACSU (O34942) (682 aa) fasta scores: E(): 3.3e-69, 33.862% id in 694 aa, and to Escherichia coli ATP-dependent DNA helicase RecG or B3652 SW:RECG_ECOLI (P24230) (693 aa) fasta scores: E(): 8.9e-63, 34.765% id in 722 aa.
       0.784
DIP1140
Putative membrane protein; No significant database matches.
       0.697
ribF
Riboflavin biosynthesis protein; Similar to Corynebacterium ammoniagenes riboflavin biosynthesis protein RibF [includes: riboflavin kinase (EC 2.7.1.26); FMN adenylyltransferase (EC 2.7.7.2)] SW:RIBF_CORAM (Q59263) (338 aa) fasta scores: E(): 9.6e-66, 54.23% id in 319 aa, and to Escherichia coli riboflavin biosynthesis protein RibF [includes: riboflavin kinase (EC 2.7.1.26); FMN adenylyltransferase (EC 2.7.7.2)] or B0025 or Z0029 or ECS0028 SW:RIBF_ECOLI (P08391) (313 aa) fasta scores: E(): 5.3e-19, 30.86% id in 311 aa.
 
   
 0.678
thiL
Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.
       0.614
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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