STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1155Putative stress related protein; Similar to Mycobacterium tuberculosis CDC1551 universal stress protein family MT1672 SWALL:AAK45942 (EMBL:AE007031) (146 aa) fasta scores: E(): 1.4e-19, 49.31% id in 146 aa, and to Rhizobium meliloti hypothetical protein RA0598 or SMA1100 SWALL:AAK65256 (EMBL:AE007249) (153 aa) fasta scores: E(): 6.8e-07, 38.37% id in 86 aa. (146 aa)    
Predicted Functional Partners:
DIP1056
Conserved hypothetical protein; Similar to Streptomyces coelicolor putative ATP/GTP-binding protein, doubtful CDS 2SC6G5.35 TR:Q9K4C0 (EMBL:AL359152) (110 aa) fasta scores: E(): 1.1e-12, 46.87% id in 96 aa, and to Mycobacterium tuberculosis hypothetical 11.3 kDa protein Rv1322 MT1363.1 or MTCY130.07 SW:YD22_MYCTU (Q10635) (98 aa) fasta scores: E(): 1.4e-10, 42.22% id in 90 aa.
      
 0.862
uvrB
Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
       0.623
DIP1054
Similar to Mycobacterium leprae hypothetical 16.5 kDa protein ML1147 or u471B SW:YD12_MYCLE (P53432) (147 aa) fasta scores: E(): 4.8e-12, 31.65% id in 139 aa, and to Mycobacterium tuberculosis hypothetical 16.6 kDa protein Rv1312 MT1352 or MTCY373.32 SW:YD12_MYCTU (Q10620) (147 aa) fasta scores: E(): 1.6e-11, 32.37% id in 139 aa, and to Streptomyces coelicolor putative secreted/membrane protein 2sc6g5.19 TR:Q9K4D3 (EMBL:AL359152) (151 aa) fasta scores: E(): 1.1e-05, 27.97% id in 143 aa.
      
 0.609
coaE
dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
  
    0.492
ptsG
Similar to Corynebacterium glutamicum PTS system, glucose-specific IIABC component PtsG SWALL:PTGA_CORGL (SWALL:Q45298) (674 aa) fasta scores: E(): 2.8e-59, 44.91% id in 688 aa, and to Staphylococcus xylosus PTS system, sucrose-specific IIBC component ScrA SWALL:PTSB_STAXY (SWALL:P51184) (480 aa) fasta scores: E(): 8e-26, 27.73% id in 494 aa.
  
    0.451
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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