STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1157Conserved hypothetical protein; N-terminal region similar to Streptomyces coelicolor hypothetical 18.8 kDa protein SC9H11.26c SWALL:Q9KYL5 (EMBL:AL356592) (177 aa) fasta scores: E(): 9.8e-11, 35.13% id in 148 aa. Note: Possible colied-coil region at C-terminal domain from residue 242 till the end. (281 aa)    
Predicted Functional Partners:
DIP1158
Putative hydrolase; Similar to Mycobacterium tuberculosis CDC1551 metallo-beta-lactamase superfamily protein MT1673 SWALL:AAK45943 (EMBL:AE007031) (264 aa) fasta scores: E(): 5e-29, 45.58% id in 204 aa, and to Streptomyces coelicolor putative hydrolase SCC54.20 SWALL:Q9Z505 (EMBL:AL035591) (218 aa) fasta scores: E(): 7.2e-26, 40.55% id in 217 aa.
 
     0.693
DIP1156
Putative helicase; Similar to Streptomyces coelicolor putative helicase protein SCE59.11c SWALL:Q9L1U3 (EMBL:AL138851) (744 aa) fasta scores: E(): 5.4e-32, 34.77% id in 788 aa, and to Clostridium acetobutylicum superfamily I DNA helicase CAC1026 SWALL:AAK79002 (EMBL:AE007618) (763 aa) fasta scores: E(): 2e-15, 23.98% id in 788 aa.
       0.670
DIP0679
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 23.7 kDa protein Rv3268 or MTCY71.08 TR:P96873 (EMBL:Z92771) (229 aa) fasta scores: E(): 7.6e-11, 31.48% id in 235 aa.
  
    0.615
DIP0392
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 32.9 kDa protein Rv0495c or MT0515 or MTCY20G9.21c SW:Y495_MYCTU (Q11160) (296 aa) fasta scores: E(): 3.6e-25, 44.07% id in 270 aa.
  
     0.591
uvrA
Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
       0.555
DIP0160
Putative membrane protein; Similar to Mycobacterium tuberculosis hypothetical 69.5 kDa protein CY13D12.26 Rv3792 or MTCY13D12.26 TR:P72058 (EMBL:Z80343) (643 aa) fasta scores: E(): 3.7e-53, 34.5% id in 652 aa.
  
     0.502
DIP0614
Putative membrane protein; Similar to Streptomyces coelicolor hypothetical 47.7 kDa protein SCE9.01 TR:Q9X8H4 (EMBL:AL049841) (436 aa) fasta scores: E(): 8.3e-18, 28.97% id in 428 aa.
  
    0.472
DIP1654
Conserved hypothetical protein; Weak similarity to C-terminus of Corynebacterium glutamicum PS1 protein precursor Csp1 SW:CSP1_CORGL (Q01377) (657 aa) fasta scores: E(): 4.3e-06, 26.943% id in 193 aa.
 
     0.458
DIP1575
Conserved hypothetical protein; Similar to N-terminal region of Deinococcus radiodurans conserved hypothetical protein DRr1631 TR:Q9RTX1 (EMBL:AE002006) (394 aa) fasta scores: E(): 4.7e-12, 31.28% id in 211 aa.
  
    0.441
DIP2207
Conserved putative secreted protein; Similar to Mycobacterium tuberculosis Csp or Rv3811 or MT3918 or MTV026.16 TR:O86334 (EMBL:Z97188) (539 aa) fasta scores: E(): 6.2e-33, 41.84% id in 411 aa, and to Streptomyces coelicolor putative secreted protein SCE34.21c TR:Q9KZK5 (EMBL:AL353862) (416 aa) fasta scores: E(): 5.6e-20, 28.74% id in 421 aa. Contains a proline/alanine rich region at residues 398-44, no present in homologues.
  
     0.439
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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