STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1178Conserved hypothetical protein; Similar to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT1731 SWALL:AAK46000 (EMBL:AE007035) (353 aa) fasta scores: E(): 1e-33, 41.06% id in 302 aa, and to Streptomyces coelicolor hypothetical 35.2 kDa protein SCI51.28c SWALL:Q9S212 (EMBL:AL109848) (343 aa) fasta scores: E(): 4e-32, 39.4% id in 302 aa. (318 aa)    
Predicted Functional Partners:
DIP1177
Conserved hypothetical protein; C-terminal region similar to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT1730 SWALL:AAK45999 (EMBL:AE007035) (250 aa) fasta scores: E(): 4e-32, 47.73% id in 243 aa, and to Streptomyces coelicolor hypothetical 22.8 kDa protein SCI51.30c SWALL:Q9S210 (EMBL:AL109848) (210 aa) fasta scores: E(): 3.1e-24, 49.17% id in 181 aa.
    
 0.952
DIP1893
Hypothetical protein; Similar to Escherichia coli glycerol dehydrogenase GldA SW:GLDA_ECOLI (P32665) (367 aa) fasta scores: E(): 6.1e-21, 29% id in 331 aa, and to Streptococcus pneumoniae glycerol dehydrogenase SP0253 TR:AAK74432 (EMBL:AE007338) (362 aa) fasta scores: E(): 3e-22, 29.64% id in 361 aa.
  
 
 0.930
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
  
 
 0.905
ppnK
Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
     
 0.846
DIP1180
Putative cytotoxin/hemolysin; Similar to Mycobacterium tuberculosis CDC1551 cytotoxin/hemolysin MT1733 SWALL:AAK46002 (EMBL:AE007035) (268 aa) fasta scores: E(): 2.2e-53, 56.56% id in 274 aa, and to Caulobacter crescentus hemolysin A CC1324 SWALL:Q9A8M9 (EMBL:AE005808) (243 aa) fasta scores: E(): 1.2e-29, 42.27% id in 246 aa.
     
 0.748
recN
DNA repair protein; May be involved in recombinational repair of damaged DNA.
     
 0.736
DIP1179
Hypothetical protein; Doubtful CDS. No strong consensus RBS usptream. No significant database matches.
       0.723
DIP1183
Putative membrane protein; Similar to Mycobacterium leprae conserved membrane protein ML1361 SWALL:Q9CC30 (EMBL:AL583921) (393 aa) fasta scores: E(): 7.2e-57, 44.16% id in 394 aa, and to Mycobacterium tuberculosis hypothetical 42.4 kDa protein Rv1697 or MTCI125.19 SWALL:O33198 (EMBL:Z98268) (393 aa) fasta scores: E(): 2.9e-56, 43.4% id in 394 aa.
       0.533
DIP1184
Putative secreted protein; Similar to Mycobacterium tuberculosis hypothetical 32.4 kDa protein Rv1698 precursor or MT1737 or MTCI125.20 SWALL:YG98_MYCTU (SWALL:P58212) (314 aa) fasta scores: E(): 4.4e-22, 31.57% id in 304 aa.
       0.520
DIP1185
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis CDC1551 MutT/NudXx family protein MT1739 SWALL:AAK46008 (EMBL:AE007036) (207 aa) fasta scores: E(): 6.7e-35, 48.3% id in 207 aa, and to Bacillus subtilis ADP-ribose pyrophosphatase NudF SWALL:ADPP_BACSU (SWALL:P54570) (185 aa) fasta scores: E(): 7.9e-15, 35.06% id in 154 aa.
  
    0.516
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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