STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1185Conserved hypothetical protein; Similar to Mycobacterium tuberculosis CDC1551 MutT/NudXx family protein MT1739 SWALL:AAK46008 (EMBL:AE007036) (207 aa) fasta scores: E(): 6.7e-35, 48.3% id in 207 aa, and to Bacillus subtilis ADP-ribose pyrophosphatase NudF SWALL:ADPP_BACSU (SWALL:P54570) (185 aa) fasta scores: E(): 7.9e-15, 35.06% id in 154 aa. (212 aa)    
Predicted Functional Partners:
nnrE
Conserved hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair o [...]
  
 0.928
xerD
Integrase/recombinase; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.
  
  
 0.900
DIP1184
Putative secreted protein; Similar to Mycobacterium tuberculosis hypothetical 32.4 kDa protein Rv1698 precursor or MT1737 or MTCI125.20 SWALL:YG98_MYCTU (SWALL:P58212) (314 aa) fasta scores: E(): 4.4e-22, 31.57% id in 304 aa.
       0.799
DIP1183
Putative membrane protein; Similar to Mycobacterium leprae conserved membrane protein ML1361 SWALL:Q9CC30 (EMBL:AL583921) (393 aa) fasta scores: E(): 7.2e-57, 44.16% id in 394 aa, and to Mycobacterium tuberculosis hypothetical 42.4 kDa protein Rv1697 or MTCI125.19 SWALL:O33198 (EMBL:Z98268) (393 aa) fasta scores: E(): 2.9e-56, 43.4% id in 394 aa.
       0.754
recN
DNA repair protein; May be involved in recombinational repair of damaged DNA.
 
   
 0.680
DIP1188
Conserved hypothetical protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
 
     0.659
DIP1187
Putative regulatory protein; Similar to Mycobacterium leprae possible regulatory protein ML1367 SWALL:Q9CC29 (EMBL:AL583921) (287 aa) fasta scores: E(): 1.8e-76, 72.72% id in 275 aa, and to Bacillus subtilis sporulation initiation inhibitor protein Soj SWALL:SOJ_BACSU (SWALL:P37522) (253 aa) fasta scores: E(): 1.2e-44, 51.21% id in 248 aa.
     
 0.644
rph
Putative ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
    
 0.589
DIP0717
Similar to Mycobacterium leprae putative ATP-dependent RNA helicase RhlE or ML0811 TR:Q9CCH3 (EMBL:AL583919) (544 aa) fasta scores: E(): 2.1e-87, 55.78% id in 441 aa, and to Klebsiella pneumoniae cold-shock dead-box protein A DeaD or CsdA SW:DEAD_KLEPN (P33906) (642 aa) fasta scores: E(): 5.7e-49, 41.91% id in 377 aa.
   
 0.568
deaD
DEAD-box helicase; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.
   
 0.568
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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