STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1195Putative pseudouridine synthase B; Similar to Mycobacterium tuberculosis hypothetical 27.6 kDa protein Rv1711 or MT1751.1 or MTCI125.33 SWALL:YH11_MYCTU (SWALL:O33210) (254 aa) fasta scores: E(): 2.8e-52, 60.74% id in 242 aa, and to Bacillus subtilis ribosomal large subunit pseudouridine synthase B RluB SWALL:RLUB_BACSU (SWALL:P35159) (229 aa) fasta scores: E(): 2e-28, 46.72% id in 229 aa. Note: Alternative start codon at residue 55. (321 aa)    
Predicted Functional Partners:
cmk
Cytidylate kinase; Similar to Mycobacterium tuberculosis cytidylate kinase Cmk or Rv1712 or MT1752 or MTCI125.34 SWALL:KCY_MYCTU (SWALL:O33211) (230 aa) fasta scores: E(): 1.9e-35, 55.45% id in 220 aa, and to Escherichia coli cytidylate kinase Cmk or MssA or B0910 or Z1256 or ECS0993 SWALL:KCY_ECOLI (SWALL:P23863) (227 aa) fasta scores: E(): 9.7e-25, 43.54% id in 209 aa.
  
 0.995
engA
Putative GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
 
  
 0.985
DIP1194
Conserved hypothetical protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.
  
  
 0.924
DIP0633
Similar to Streptomyces coelicolor putative exodeoxyribonuclease SCE87.25c TR:Q9RKB3 (EMBL:AL132674) (274 aa) fasta scores: E(): 2.6e-27, 44.3% id in 307 aa.
  
    0.700
DIP2047
Putative exonuclease; Similar to Streptomyces coelicolor putative exonuclease SC3A7.09 SWALL:O86610 (EMBL:AL031155) (259 aa) fasta scores: E(): 4.4e-32, 51.93% id in 258 aa, and to Mycobacterium tuberculosis CDC1551 exodeoxyribonuclease III MT0442 SWALL:AAK44665 (EMBL:AE006947) (291 aa) fasta scores: E(): 1.2e-25, 54.16% id in 264 aa.
  
    0.700
DIP1188
Conserved hypothetical protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
  
  
 0.639
bioD2
Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.
   
   0.592
bioA
Similar to Corynebacterium glutamicum adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA SWALL:BIOA_CORGL (SWALL:P46395) (423 aa) fasta scores: E(): 7.2e-95, 55.68% id in 422 aa, and to Escherichia coli adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA or B0774 SWALL:BIOA_ECOLI (SWALL:P12995) (429 aa) fasta scores: E(): 3.5e-87, 52.98% id in 419 aa; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
       0.557
dcuB
Similar to Escherichia coli anaerobic C4-dicarboxylate transporter DcuB or GenF or B4123 or Z5725 or ECS5105 SWALL:DCUB_ECOLI (SWALL:P14409) (446 aa) fasta scores: E(): 4.3e-91, 54.5% id in 444 aa, and to Wolinella succinogenes C4-dicarboxylate membrane transporter DcuB SWALL:Q9ZEN8 (EMBL:AJ131242) (452 aa) fasta scores: E(): 4e-94, 54.12% id in 449 aa.
       0.533
recN
DNA repair protein; May be involved in recombinational repair of damaged DNA.
 
     0.508
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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