STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1206Conserved hypothetical protein; Similar to Mycobacterium leprae hypothetical 18.1 kDa protein ML2074 or MLCB1788.34c SWALL:O32917 (EMBL:AL008609) (164 aa) fasta scores: E(): 7.8e-13, 32.02% id in 153 aa, and to Mycobacterium tuberculosis hypothetical 18.1 kDa protein Rv1829 or MT1877 or MTCY1A11.14c SWALL:YI29_MYCTU (SWALL:Q50604) (164 aa) fasta scores: E(): 9.1e-13, 34.07% id in 135 aa. (195 aa)    
Predicted Functional Partners:
DIP1207
Putative transcriptional regulator; Similar to Mycobacterium tuberculosis hypothetical 24.0 kDa protein Rv1830 or MT1879 or MTCY1A11.13c SWALL:YI30_MYCTU (SWALL:Q50603) (225 aa) fasta scores: E(): 1.5e-41, 72.98% id in 174 aa, and to Bacillus subtilis regulatory protein GlnR SWALL:GLNR_BACSU (SWALL:P37582) (135 aa) fasta scores: E(): 0.22, 29.16% id in 72 aa.
     
 0.943
DIP1205
Putative merR-family regulatory protein; Similar to Streptomyces coelicolor hypothetical 26.5 kDa protein SC1A8A.03c SWALL:Q9KZP9 (EMBL:AL353861) (246 aa) fasta scores: E(): 1.4e-27, 41.44% id in 222 aa, and to Mycobacterium tuberculosis hypothetical 26.4 kDa protein Rv1828 or MT1876 or MTCY1A11.15c SWALL:YI28_MYCTU (SWALL:Q50605) (247 aa) fasta scores: E(): 1.2e-14, 40.25% id in 236 aa.
     
 0.841
odhI
Putative signal transduction protein; An essential component of the PknG signaling pathway. When unphosphorylated, it inhibits the activity of 2-oxoglutarate dehydrogenase. When phosphorylated it does not inhibit 2-oxoglutarate dehydrogenase (By similarity).
 
     0.663
secA2
Putative preprotein translocase; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
     
 0.628
arc
Putative AAA protein family ATPase; Similar to, although shorter in its N-terminal region than Streptomyces coelicolor AAA protein family ATPase Arc SWALL:Q9RJ58 (EMBL:AL132648) (588 aa) fasta scores: E(): 3e-76, 54.14% id in 519 aa, and to, although shorter in its N-terminal region than Mycobacterium leprae putative AAA-family ATPase ML1316 or MLCB2533.12 or A2126A or B2126_C1_167 SWALL:YL15_MYCLE (SWALL:P46509) (609 aa) fasta scores: E(): 2.1e-58, 54.99% id in 531 aa.
   
    0.482
DIP1201
Similar to Streptomyces coelicolor conserved hypothetical protein SCI52.19 SWALL:Q9AD90 (EMBL:AL590507) (124 aa) fasta scores: E(): 2.7e-20, 49.58% id in 121 aa, and to Escherichia coli hypothetical protein YchJ or B1233 SWALL:YCHJ_ECOLI (SWALL:P37052) (152 aa) fasta scores: E(): 7.6e-15, 38.71% id in 124 aa.
       0.465
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.