STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1207Putative transcriptional regulator; Similar to Mycobacterium tuberculosis hypothetical 24.0 kDa protein Rv1830 or MT1879 or MTCY1A11.13c SWALL:YI30_MYCTU (SWALL:Q50603) (225 aa) fasta scores: E(): 1.5e-41, 72.98% id in 174 aa, and to Bacillus subtilis regulatory protein GlnR SWALL:GLNR_BACSU (SWALL:P37582) (135 aa) fasta scores: E(): 0.22, 29.16% id in 72 aa. (186 aa)    
Predicted Functional Partners:
DIP1206
Conserved hypothetical protein; Similar to Mycobacterium leprae hypothetical 18.1 kDa protein ML2074 or MLCB1788.34c SWALL:O32917 (EMBL:AL008609) (164 aa) fasta scores: E(): 7.8e-13, 32.02% id in 153 aa, and to Mycobacterium tuberculosis hypothetical 18.1 kDa protein Rv1829 or MT1877 or MTCY1A11.14c SWALL:YI29_MYCTU (SWALL:Q50604) (164 aa) fasta scores: E(): 9.1e-13, 34.07% id in 135 aa.
     
 0.943
rpoZ
Putative DNA-directed RNA polymerase omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
 
   0.858
whiB-2
Putative regulatory protein; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
  
   
 0.826
secG
Protein transport/translocation membrane protein; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.
  
    0.774
whiB-3
Putative transcriptional regulator; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
  
     0.773
DIP1402
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT2773 TR:AAK47088 (EMBL:AE007106) (100 aa) fasta scores: E(): 1.6e-17, 57% id in 100 aa, and to Streptomyces coelicolor hypothetical 11.0 kDa protein SC2E9.05 TR:O54130 (EMBL:AL021530) (98 aa) fasta scores: E(): 4.9e-14, 49.49% id in 99 aa.
  
     0.772
rbpA
Conserved hypothetical protein; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. Belongs to the RNA polymerase-binding protein RbpA family.
 
     0.768
DIP1205
Putative merR-family regulatory protein; Similar to Streptomyces coelicolor hypothetical 26.5 kDa protein SC1A8A.03c SWALL:Q9KZP9 (EMBL:AL353861) (246 aa) fasta scores: E(): 1.4e-27, 41.44% id in 222 aa, and to Mycobacterium tuberculosis hypothetical 26.4 kDa protein Rv1828 or MT1876 or MTCY1A11.15c SWALL:YI28_MYCTU (SWALL:Q50605) (247 aa) fasta scores: E(): 1.2e-14, 40.25% id in 236 aa.
 
   
 0.767
DIP1514
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 12.2 kDa protein Rv2901c or MT2969 or MTCY274.32c SW:YT01_MYCTU (Q10822) (101 aa) fasta scores: E(): 3.7e-31, 70.29% id in 101 aa, and to Streptomyces coelicolor hypothetical 12.3 kDa protein SC2E1.18 TR:O69889 (EMBL:AL023797) (102 aa) fasta scores: E(): 2.9e-27, 67% id in 100 aa.
  
     0.753
whiA
Conserved hypothetical protein; Involved in cell division and chromosome segregation.
  
   
 0.741
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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