STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1211Putative membrane protein; Similar to Mycobacterium tuberculosis hypothetical 48.1 kDa protein Rv1842c or MT1890 or MTCY1A11.02 or MTCY359.31 SWALL:YI42_MYCTU (SWALL:Q50592) (455 aa) fasta scores: E(): 8.3e-77, 49.55% id in 444 aa, and to Myxococcus xanthus hemolysin TlyC SWALL:AAK64446 (EMBL:AF377339) (463 aa) fasta scores: E(): 9.4e-38, 34.74% id in 449 aa. (464 aa)    
Predicted Functional Partners:
DIP1210
Putative membrane protein; Similar to Rhodococcus fascians hypothetical 40.3 kDa protein SWALL:Q9AE57 (EMBL:AJ301559) (380 aa) fasta scores: E(): 5.4e-62, 50.28% id in 348 aa, to Streptomyces coelicolor putative integral membrane protein SC6D7.04 SWALL:Q9RKZ3 (EMBL:AL133213) (347 aa) fasta scores: E(): 8.2e-47, 40.93% id in 342 aa, and to Bacillus subtilis hypothetical 49.9 kDa protein in citA-sspB intergenic region YhdP SWALL:YHDP_BACSU (SWALL:O07585) (444 aa) fasta scores: E(): 5.3e-34, 34.48% id in 348 aa.
 
   
0.959
DIP1209
Conserved hypothetical protein; Similar to Rhodococcus fascians hypothetical 34.0 kDa protein SWALL:Q9AE56 (EMBL:AJ301559) (304 aa) fasta scores: E(): 2.2e-46, 44.91% id in 285 aa.
       0.842
DIP1212
Putative RNA helicase; Similar to Streptomyces coelicolor SC10A5.25c protein SWALL:O54116 (EMBL:AL021529) (498 aa) fasta scores: E(): 6.5e-63, 46.93% id in 424 aa, and to Escherichia coli putative ATP-dependent RNA helicase RhlE or B0797 SWALL:RHLE_ECOLI (SWALL:P25888) (454 aa) fasta scores: E(): 7.6e-44, 36.06% id in 452 aa.
       0.796
DIP1208
Putative secreted protein; No significant database matches.
       0.780
gnd
6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
       0.656
DIP1214
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 15.1 kDa protein Rv1847 or MT1895 or MTCY359.26c SWALL:YI47_MYCTU (SWALL:P95162) (140 aa) fasta scores: E(): 1.6e-08, 34.67% id in 124 aa, and to Pseudomonas aeruginosa hypothetical protein PA1618 SWALL:YG18_PSEAE (SWALL:Q9I3A4) (145 aa) fasta scores: E(): 2e-05, 32.82% id in 131 aa.
       0.573
ybeY
Conserved hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
  
    0.466
dnaJ2
Chaperone protein 2; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK [...]
 
     0.428
DIP1718
Putative PhoH-like protein; Similar to Mycobacterium tuberculosis PhoH-like protein Rv2368c or MT2437 or MTCY27.12 SW:PHOL_MYCTU (O05830) (352 aa) fasta scores: E(): 2.2e-66, 63.25% id in 313 aa, and to Bacillus subtilis PhoH-like protein PhoH SW:PHOL_BACSU (P46343) (319 aa) fasta scores: E(): 2.9e-52, 52.47% id in 303 aa.
  
    0.413
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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