STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gnd6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (484 aa)    
Predicted Functional Partners:
zwf
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
 
 0.997
DIP0254
Putative transferase; Similar to Streptomyces coelicolor putative gluconokinase SCI52.21 TR:Q9AD88 (EMBL:AL590507) (175 aa) fasta scores: E(): 4.2e-33, 60.39% id in 154 aa, and to Escherichia coli thermosensitive gluconokinase IdnK or GntV or B4268 SW:IDNK_ECOLI (P39208) (187 aa) fasta scores: E(): 3e-20, 44.15% id in 154 aa.
   
 0.992
rpe
Similar to Mycobacterium tuberculosis ribulose-phosphate 3-epimerase Rpe or Rv1408 or MT1452 or MTCY21B4.25 SWALL:RPE_MYCTU (SWALL:P71676) (229 aa) fasta scores: E(): 2e-49, 58.63% id in 220 aa, and to Escherichia coli ribulose-phosphate 3-epimerase Rpe or Dod or B3386 or Z4739 or ECS4228 SWALL:RPE_ECOLI (SWALL:P32661) (225 aa) fasta scores: E(): 1.3e-30, 43.19% id in 213 aa.
   
 0.949
pgl
Putative phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
 
 
 0.948
DIP1796
Putative ribose/galactose isomerase; Similar to Staphylococcus aureus galactose-6-phosphate isomerase subunit LacB SW:LACB_STAAU (P26592) (171 aa) fasta scores: E(): 2e-13, 36.53% id in 156 aa, and to Mycobacterium tuberculosis putative isomerase Rv2465c TR:AAK46840 (EMBL:AL021246) (159 aa) fasta scores: E(): 4.1e-45, 76.77% id in 155 aa.
    
 0.915
tkt
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 
 0.866
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily.
  
 
 0.843
ptsG
Similar to Corynebacterium glutamicum PTS system, glucose-specific IIABC component PtsG SWALL:PTGA_CORGL (SWALL:Q45298) (674 aa) fasta scores: E(): 2.8e-59, 44.91% id in 688 aa, and to Staphylococcus xylosus PTS system, sucrose-specific IIBC component ScrA SWALL:PTSB_STAXY (SWALL:P51184) (480 aa) fasta scores: E(): 8e-26, 27.73% id in 494 aa.
     
 0.781
DIP1212
Putative RNA helicase; Similar to Streptomyces coelicolor SC10A5.25c protein SWALL:O54116 (EMBL:AL021529) (498 aa) fasta scores: E(): 6.5e-63, 46.93% id in 424 aa, and to Escherichia coli putative ATP-dependent RNA helicase RhlE or B0797 SWALL:RHLE_ECOLI (SWALL:P25888) (454 aa) fasta scores: E(): 7.6e-44, 36.06% id in 452 aa.
  
 
 0.715
DIP1214
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 15.1 kDa protein Rv1847 or MT1895 or MTCY359.26c SWALL:YI47_MYCTU (SWALL:P95162) (140 aa) fasta scores: E(): 1.6e-08, 34.67% id in 124 aa, and to Pseudomonas aeruginosa hypothetical protein PA1618 SWALL:YG18_PSEAE (SWALL:Q9I3A4) (145 aa) fasta scores: E(): 2e-05, 32.82% id in 131 aa.
       0.695
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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