STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rbpAConserved hypothetical protein; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. Belongs to the RNA polymerase-binding protein RbpA family. (129 aa)    
Predicted Functional Partners:
rpoZ
Putative DNA-directed RNA polymerase omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
 
   0.999
rpoB
DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.998
rpoC
DNA-directed RNA polymerase beta' chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.997
DIP1974
Putative CarD-like transcriptional factor; N-terminal region is similar to Mycobacterium tuberculosis putative transcriptional factor Rv3583c TR:O53568 (EMBL:AL022075) (162 aa) fasta scores: E(): 6.8e-38, 71.69% id in 159 aa, and to Mycobacterium leprae putative transcription factor ML0320 TR:Q9CCW7 (EMBL:AL583918) (165 aa) fasta scores: E(): 1.2e-37, 70.44% id in 159 aa.
    
 
 0.996
sigA
RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
    
 
 0.990
sigB
RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
    
 
 0.990
rpoA
DNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.988
DIP1402
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT2773 TR:AAK47088 (EMBL:AE007106) (100 aa) fasta scores: E(): 1.6e-17, 57% id in 100 aa, and to Streptomyces coelicolor hypothetical 11.0 kDa protein SC2E9.05 TR:O54130 (EMBL:AL021530) (98 aa) fasta scores: E(): 4.9e-14, 49.49% id in 99 aa.
  
     0.774
DIP1243
Conserved hypothetical protein; Similar to Rhodococcus erythropolis ORF11 SWALL:P72265 (EMBL:Z82004) (326 aa) fasta scores: E(): 1.3e-24, 31.42% id in 315 aa, and to Mycobacterium tuberculosis hypothetical 33.8 kDa protein Rv2095c precursor or MT2156 or MTCY49.35c SWALL:YK95_MYCTU (SWALL:Q10704) (316 aa) fasta scores: E(): 3.4e-24, 31.57% id in 304 aa.
 
 
   0.770
DIP1207
Putative transcriptional regulator; Similar to Mycobacterium tuberculosis hypothetical 24.0 kDa protein Rv1830 or MT1879 or MTCY1A11.13c SWALL:YI30_MYCTU (SWALL:Q50603) (225 aa) fasta scores: E(): 1.5e-41, 72.98% id in 174 aa, and to Bacillus subtilis regulatory protein GlnR SWALL:GLNR_BACSU (SWALL:P37582) (135 aa) fasta scores: E(): 0.22, 29.16% id in 72 aa.
 
     0.768
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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