STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
lntPutative transferase/membrane protein; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. (519 aa)    
Predicted Functional Partners:
ppm1
Similar to Mycobacterium smegmatis putative polyprenol phosphate mannosyl transferase 1 Ppm1 SWALL:Q9F408 (EMBL:AJ294477) (265 aa) fasta scores: E(): 1.6e-56, 61.6% id in 237 aa, and to Schizosaccharomyces pombe dolichol-phosphate mannosyltransferase Dpm1 or SPAC31G5.16c SWALL:O14466 (EMBL:AF007873) (236 aa) fasta scores: E(): 1.2e-24, 39.54% id in 220 aa.
    
 0.947
DIP1228
Putative membrane protein; Similar to Mycobacterium tuberculosis hypothetical 18.1 kDa protein Rv2053c or MTV018.40c or MTCY63A.07 SWALL:O53495 (EMBL:AL021899) (175 aa) fasta scores: E(): 0.00056, 29.07% id in 172 aa, and to Rhizobium meliloti hypothetical transmembrane protein R00007 or SCM02787 SWALL:CAC41394 (EMBL:AL591782) (191 aa) fasta scores: E(): 0.044, 29.06% id in 117 aa.
  
    0.854
lgt
Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.
 
  
 0.767
cobN
Putative cobalamin biosynthesis related protein; Similar to Mycobacterium tuberculosis CobN or Rv2062c or MT2121 or MTCY49.01c or MTV019.03 SWALL:AAK46401 (EMBL:AL021922) (1195 aa) fasta scores: E(): 0, 62.22% id in 1215 aa, and to Methanococcus jannaschii hypothetical protein MJ0908 SWALL:Q58318 (EMBL:U67534) (1232 aa) fasta scores: E(): 5.1e-109, 36.48% id in 1258 aa.
       0.754
lspA
Putative lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.
     
 0.716
DIP1231
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis CDC1551 CobG-related protein MT2124 SWALL:AAK46404 (EMBL:AE007063) (363 aa) fasta scores: E(): 5.1e-43, 39.56% id in 369 aa.
 
   
 0.594
DIP1230
Hypothetical protein; Doubtful CDS. No strong consensus RBS usptream. No significant database matches.
       0.477
secD
Putative protein export membrane protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
 
   
 0.449
DIP1385
Conserved hypothetical protein; Similar to Mycobacterium leprae hypothetical 35.4 kDa protein ML0453 or MLCl581.15c SWALL:O07148 (EMBL:Z96801) (320 aa) fasta scores: E(): 5.5e-52, 47.33% id in 300 aa, and to Streptomyces coelicolor putative acyltransferase SCL2.16c SWALL:Q9L283 (EMBL:AL137778) (311 aa) fasta scores: E(): 1.4e-37, 43.44% id in 290 aa.
  
   
 0.433
glnD
Similar to Corynebacterium glutamicum [protein-PII] uridylyltransferase GlnD SW:GLND_CORGL (Q9X706) (692 aa) fasta scores: E(): 7.1e-126, 52.6% id in 709 aa, and to Escherichia coli [protein-PII] uridylyltransferase GlnD or B0167 SW:GLND_ECOLI (P27249) (890 aa) fasta scores: E(): 1.1e-05, 25.76% id in 555 aa. Note It might have two alternative start codons at residues 3 or 4.
  
     0.420
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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