STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1231Conserved hypothetical protein; Similar to Mycobacterium tuberculosis CDC1551 CobG-related protein MT2124 SWALL:AAK46404 (EMBL:AE007063) (363 aa) fasta scores: E(): 5.1e-43, 39.56% id in 369 aa. (397 aa)    
Predicted Functional Partners:
cobIJ
Similar to Mycobacterium tuberculosis cobalamin biosynthesis protein [includes: precorrin-2 C20-methyltransferase; precorrin-3 methylase] CobIJ or Rv2066 or MT2126 or MTCY49.05 SWALL:COBI_MYCTU (SWALL:Q10677) (508 aa) fasta scores: E(): 3.6e-88, 50.7% id in 495 aa, C-terminal region to Rhodobacter capsulatus precorrin-3 methylase SWALL:O68097 (EMBL:AF010496) (245 aa) fasta scores: E(): 1.1e-34, 48.14% id in 243 aa, and N-terminal region to Pseudomonas aeruginosa precorrin-2 methyltransferase CobI or PA2904 SWALL:Q9HZU3 (EMBL:AE004716) (250 aa) fasta scores: E(): 1.4e-33, 43.3% id in 254 aa.
 
 
 0.997
cobH
Similar to Pseudomonas denitrificans precorrin-8X methylmutase CobH SWALL:COBH_PSEDE (SWALL:P21638) (210 aa) fasta scores: E(): 1e-40, 59.9% id in 207 aa, and to Streptomyces coelicolor putative precorrin-8X methylmutase SCE39.32 SWALL:Q9X8F5 (EMBL:AL049573) (218 aa) fasta scores: E(): 8.2e-44, 62.08% id in 211 aa.
  
 0.983
DIP0495
Putative molybdenum ABC transport system (integral membrane and ATP-binding proteins); N-terminal region similar to Mycobacterium tuberculosis molybdenum transport system permease protein ModB or Rv1858 or MT1906 or MTCY359.15c SW:MODB_MYCTU (P95156) blast scores: E(): 2e-32, score: 353 37% id, and C-terminal region to Mycobacterium tuberculosis molybdenum transport ATP-binding protein ModC or Rv1859 or MT1907 or MTCY359.14 SW:MODC_MYCTU (P95155) blast scores: E(): 1e-17, score: 93 28% id.
  
  
 0.938
DIP1236
Similar to Mycobacterium tuberculosis precorrin-6Y C5,15-methyltransferase [decarboxylating] CobL or Rv2072c or MT2132 or MTCY49.11c SWALL:COBL_MYCTU (SWALL:Q10671) (390 aa) fasta scores: E(): 5.8e-57, 44.22% id in 398 aa, and to Pseudomonas denitrificans precorrin-6Y C5,15-methyltransferase [decarboxylating] CobL SWALL:COBL_PSEDE (SWALL:P21921) (413 aa) fasta scores: E(): 1.5e-47, 39.5% id in 405 aa.
 
  
 0.891
DIP0402
Similar to Mycobacterium leprae possible uroporphyrin-III C-methyltransferase HemD or ML2420 TR:Q9CB60 (EMBL:AL583925) (563 aa) fasta scores: E(): 9.3e-91, 52.81% id in 551 aa.
  
  
 0.884
cobN
Putative cobalamin biosynthesis related protein; Similar to Mycobacterium tuberculosis CobN or Rv2062c or MT2121 or MTCY49.01c or MTV019.03 SWALL:AAK46401 (EMBL:AL021922) (1195 aa) fasta scores: E(): 0, 62.22% id in 1215 aa, and to Methanococcus jannaschii hypothetical protein MJ0908 SWALL:Q58318 (EMBL:U67534) (1232 aa) fasta scores: E(): 5.1e-109, 36.48% id in 1258 aa.
 
   
 0.841
cobK
precorrin-6X reductase; Similar to Rhodococcus erythropolis precorrin-6X reductase CobK SWALL:COBK_RHOER (SWALL:Q53139) (248 aa) fasta scores: E(): 1.6e-41, 50% id in 244 aa, and to Mycobacterium tuberculosis precorrin-6X reductase CobK or Rv2070c or MT2130 or MTCY49.09c SWALL:COBK_MYCTU (SWALL:Q10680) (244 aa) fasta scores: E(): 1.2e-36, 47.54% id in 244 aa.
 
   
 0.790
DIP1484
Similar to Propionibacterium freudenreichii shermanii uroporphyrinogen III methyltransferase CobA TR:Q51720 (EMBL:U13043) (257 aa) fasta scores: E(): 1.6e-37, 47.05% id in 238 aa, and to Bacillus megaterium uroporphyrinogen III methylase CysGA TR:O87699 (EMBL:AJ000758) (243 aa) fasta scores: E(): 4.5e-32, 44.58% id in 240 aa.
  
  
 0.766
DIP0822
Putative cobalamin synthesis related protein; Similar to Pseudomonas denitrificans CobF protein SW:COBF_PSEDE (P21636) (261 aa) fasta scores: E(): 6.9e-32, 39.68% id in 252 aa.
 
  
 0.749
DIP0703
Putative oxidoreductase; Similar to Mycobacterium tuberculosis hypothetical 40.8 kDa protein Rv3230c or MTCY20B11.05c TR:O05875 (EMBL:Z95121) (380 aa) fasta scores: E(): 4.8e-60, 49.14% id in 350 aa, and to Escherichia coli NADH oxidoreductase Hcr or B0872 SW:HCR_ECOLI (P75824) (322 aa) fasta scores: E(): 1.9e-13, 28.71% id in 296 aa.
 
 
 
 0.599
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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