STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1238Putative dipeptidase; Similar to Mycobacterium tuberculosis probable dipeptidase Rv2089c or MT2150 or MTCY49.29c SWALL:YK89_MYCTU (SWALL:Q10698) (375 aa) fasta scores: E(): 3.1e-56, 49.86% id in 377 aa, and to Halobacterium sp probable peptidase PepQ1 or Vng0723g SWALL:Q9HRF6 (EMBL:AE005016) (369 aa) fasta scores: E(): 2.2e-37, 38.62% id in 378 aa. (379 aa)    
Predicted Functional Partners:
DIP1237
Similar to Mycobacterium tuberculosis putative oxidoreductase Rv2073c or MT2133 or MTCY49.12c SWALL:YK73_MYCTU (SWALL:Q10681) (249 aa) fasta scores: E(): 1.3e-38, 46.82% id in 252 aa, and to Streptomyces coelicolor putative short-chain dehydrogenase SC5G8.09c SWALL:Q9KZA5 (EMBL:AL353872) (256 aa) fasta scores: E(): 3.1e-27, 37.94% id in 253 aa.
  
    0.840
DIP1239
Putative helicase; Similar to Mycobacterium tuberculosis probable helicase HelY or Rv2092c or MT2153 or MTCY49.30c SWALL:HELY_MYCTU (SWALL:Q10701) (906 aa) fasta scores: E(): 4.5e-69, 48.87% id in 933 aa, and to Synechocystis sp antiviral protein Ski2 or SLR0451 SWALL:P74686 (EMBL:D90917) (1006 aa) fasta scores: E(): 2.3e-27, 29.42% id in 1040 aa.
       0.732
DIP1236
Similar to Mycobacterium tuberculosis precorrin-6Y C5,15-methyltransferase [decarboxylating] CobL or Rv2072c or MT2132 or MTCY49.11c SWALL:COBL_MYCTU (SWALL:Q10671) (390 aa) fasta scores: E(): 5.8e-57, 44.22% id in 398 aa, and to Pseudomonas denitrificans precorrin-6Y C5,15-methyltransferase [decarboxylating] CobL SWALL:COBL_PSEDE (SWALL:P21921) (413 aa) fasta scores: E(): 1.5e-47, 39.5% id in 405 aa.
       0.723
DIP1929
Similar to Thermus aquaticus aspartate aminotransferase AspC SW:AAT_THETH (Q56232) (385 aa) fasta scores: E(): 1.1e-29, 32.95% id in 352 aa, and to Mycobacterium tuberculosis hypothetical protein Rv3565 TR:P96847 (EMBL:Z92774) (388 aa) fasta scores: E(): 6.4e-68, 48.15% id in 380 aa.
    
 
 0.713
cobK
precorrin-6X reductase; Similar to Rhodococcus erythropolis precorrin-6X reductase CobK SWALL:COBK_RHOER (SWALL:Q53139) (248 aa) fasta scores: E(): 1.6e-41, 50% id in 244 aa, and to Mycobacterium tuberculosis precorrin-6X reductase CobK or Rv2070c or MT2130 or MTCY49.09c SWALL:COBK_MYCTU (SWALL:Q10680) (244 aa) fasta scores: E(): 1.2e-36, 47.54% id in 244 aa.
       0.681
cobM
Similar to Pseudomonas denitrificans precorrin-4 C11-methyltransferase CobM SWALL:COBM_PSEDE (SWALL:P21922) (253 aa) fasta scores: E(): 5.4e-46, 55.37% id in 251 aa, and to Rhodococcus erythropolis precorrin-4 C11-methyltransferase CobM SWALL:COBM_RHOER (SWALL:Q53138) (249 aa) fasta scores: E(): 3.4e-57, 61.04% id in 249 aa.
       0.681
DIP0554
Putative subtilisin-like cell wall associated serine protease (mycosin); Similar to Streptomyces coelicolor serine protease SC3C3.08 TR:O86642 (EMBL:AL031231) (413 aa) fasta scores: E(): 4e-11, 32.37% id in 278 aa and to Mycobacterium tuberculosis hypothetical 46.0 kDa protein Rv3449 or MTCY13E12.02 or MT3555 SWALL:O06316 (EMBL:Z95390) (455 aa) fasta scores: E(): 4.7e-10, 38.11% id in 307 aa.
     
 0.495
DIP2298
Putative oxidoreductase; Similar to Bacillus subtilis hypothetical oxidoreductase YoxD SWALL:YOXD_BACSU (SWALL:P14802) (238 aa) fasta scores: E(): 2.2e-09, 28.57% id in 231 aa, and to Rhizobium sp putative short-chain type dehydrogenase/reductase SWALL:Y4EK_RHISN (SWALL:P55434) (248 aa) fasta scores: E(): 2.3e-09, 30% id in 210 aa.
 
 
 
 0.491
DIP1240
Putative tRNA/rRNA methyltransferase; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
       0.445
trpC1
Similar to Corynebacterium glutamicum tryptophan biosynthesis protein TrpCF [includes: indole-3-glycerol phosphate synthase trpC SW:TRPC_CORGL (P06560) (474 aa) fasta scores: E(): 7.5e-121, 70.15% id in 459 aa, and to Escherichia coli tryptophan biosynthesis protein TrpCF [includes: indole-3-glycerol phosphate synthase TrpC or b1262 SW:TRPC_ECOLI (P00909) (452 aa) fasta scores: E(): 3.9e-58, 41.7% id in 482 aa. Note overlap with upstream gene suggesting possible downstream translational start codon; Belongs to the TrpF family.
  
  
 0.436
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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