STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1239Putative helicase; Similar to Mycobacterium tuberculosis probable helicase HelY or Rv2092c or MT2153 or MTCY49.30c SWALL:HELY_MYCTU (SWALL:Q10701) (906 aa) fasta scores: E(): 4.5e-69, 48.87% id in 933 aa, and to Synechocystis sp antiviral protein Ski2 or SLR0451 SWALL:P74686 (EMBL:D90917) (1006 aa) fasta scores: E(): 2.3e-27, 29.42% id in 1040 aa. (930 aa)    
Predicted Functional Partners:
DIP0969
Similar to Mycobacterium tuberculosis CDC1551 GTP-binding elongation factor family protein MT1202 TR:AAK45459 (EMBL:AE006997) (628 aa) fasta scores: E(): 6.7e-148, 67.88% id in 629 aa, and to Escherichia coli GTP-binding protein TypA/BipA TypA or BipA or B3871 SW:TYPA_ECOLI (P32132) (591 aa) fasta scores: E(): 3.3e-58, 46.49% id in 613 aa.
      
 0.762
DIP1237
Similar to Mycobacterium tuberculosis putative oxidoreductase Rv2073c or MT2133 or MTCY49.12c SWALL:YK73_MYCTU (SWALL:Q10681) (249 aa) fasta scores: E(): 1.3e-38, 46.82% id in 252 aa, and to Streptomyces coelicolor putative short-chain dehydrogenase SC5G8.09c SWALL:Q9KZA5 (EMBL:AL353872) (256 aa) fasta scores: E(): 3.1e-27, 37.94% id in 253 aa.
       0.743
DIP1238
Putative dipeptidase; Similar to Mycobacterium tuberculosis probable dipeptidase Rv2089c or MT2150 or MTCY49.29c SWALL:YK89_MYCTU (SWALL:Q10698) (375 aa) fasta scores: E(): 3.1e-56, 49.86% id in 377 aa, and to Halobacterium sp probable peptidase PepQ1 or Vng0723g SWALL:Q9HRF6 (EMBL:AE005016) (369 aa) fasta scores: E(): 2.2e-37, 38.62% id in 378 aa.
       0.743
DIP1236
Similar to Mycobacterium tuberculosis precorrin-6Y C5,15-methyltransferase [decarboxylating] CobL or Rv2072c or MT2132 or MTCY49.11c SWALL:COBL_MYCTU (SWALL:Q10671) (390 aa) fasta scores: E(): 5.8e-57, 44.22% id in 398 aa, and to Pseudomonas denitrificans precorrin-6Y C5,15-methyltransferase [decarboxylating] CobL SWALL:COBL_PSEDE (SWALL:P21921) (413 aa) fasta scores: E(): 1.5e-47, 39.5% id in 405 aa.
       0.658
cobK
precorrin-6X reductase; Similar to Rhodococcus erythropolis precorrin-6X reductase CobK SWALL:COBK_RHOER (SWALL:Q53139) (248 aa) fasta scores: E(): 1.6e-41, 50% id in 244 aa, and to Mycobacterium tuberculosis precorrin-6X reductase CobK or Rv2070c or MT2130 or MTCY49.09c SWALL:COBK_MYCTU (SWALL:Q10680) (244 aa) fasta scores: E(): 1.2e-36, 47.54% id in 244 aa.
       0.632
cobM
Similar to Pseudomonas denitrificans precorrin-4 C11-methyltransferase CobM SWALL:COBM_PSEDE (SWALL:P21922) (253 aa) fasta scores: E(): 5.4e-46, 55.37% id in 251 aa, and to Rhodococcus erythropolis precorrin-4 C11-methyltransferase CobM SWALL:COBM_RHOER (SWALL:Q53138) (249 aa) fasta scores: E(): 3.4e-57, 61.04% id in 249 aa.
       0.632
arc
Putative AAA protein family ATPase; Similar to, although shorter in its N-terminal region than Streptomyces coelicolor AAA protein family ATPase Arc SWALL:Q9RJ58 (EMBL:AL132648) (588 aa) fasta scores: E(): 3e-76, 54.14% id in 519 aa, and to, although shorter in its N-terminal region than Mycobacterium leprae putative AAA-family ATPase ML1316 or MLCB2533.12 or A2126A or B2126_C1_167 SWALL:YL15_MYCLE (SWALL:P46509) (609 aa) fasta scores: E(): 2.1e-58, 54.99% id in 531 aa.
 
     0.604
secG
Protein transport/translocation membrane protein; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.
  
     0.549
DIP1240
Putative tRNA/rRNA methyltransferase; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
       0.545
whiB-3
Putative transcriptional regulator; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
  
     0.527
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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