STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
arcPutative AAA protein family ATPase; Similar to, although shorter in its N-terminal region than Streptomyces coelicolor AAA protein family ATPase Arc SWALL:Q9RJ58 (EMBL:AL132648) (588 aa) fasta scores: E(): 3e-76, 54.14% id in 519 aa, and to, although shorter in its N-terminal region than Mycobacterium leprae putative AAA-family ATPase ML1316 or MLCB2533.12 or A2126A or B2126_C1_167 SWALL:YL15_MYCLE (SWALL:P46509) (609 aa) fasta scores: E(): 2.1e-58, 54.99% id in 531 aa. (509 aa)    
Predicted Functional Partners:
pup
Conserved hypothetical protein; Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
 
 
 
 0.999
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
   
 0.987
pafA
Conserved hypothetical protein; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side- chain amino group of a substrate lysine.
 
  
 0.974
DIP1247
Conserved hypothetical protein; Similar to Rhodococcus erythropolis similar to ORF6 SWALL:Q53081 (EMBL:U26422) (499 aa) fasta scores: E(): 2.2e-72, 48.04% id in 512 aa, and to Frankia spACN14A/ts-r. hypothetical 56.4 kDa protein SWALL:Q9RAW9 (EMBL:AF142435) (505 aa) fasta scores: E(): 3.8e-51, 47.36% id in 494 aa.
 
  
 0.971
DIP0307
Similar to Mycobacterium tuberculosis CDC1551 serine protease MT3772 TR:AAK48139 (EMBL:AE007175) (397 aa) fasta scores: E(): 1.5e-47, 38.19% id in 398 aa.
  
 
 0.832
DIP0856
Putative serine protease; Similar to Mycobacterium tuberculosis putative serine protease Rv0983 or MTV044.11 SWALL:O53896 (EMBL:AL021999) (464 aa) fasta scores: E(): 3.8e-46, 43.84% id in 406 aa, and to Brucella abortus probable serine protease do-like precursor DegP or HtrA SWALL:DEGP_BRUAB (SWALL:Q44597) (513 aa) fasta scores: E(): 7.6e-25, 44.56% id in 285 aa.
    
 0.807
DIP1249
Conserved hypothetical protein; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
 
     0.804
DIP1244
Conserved hypothetical protein; Similar to Rhodococcus erythropolis ORF10 SWALL:P72264 (EMBL:Z82004) (330 aa) fasta scores: E(): 6.6e-20, 31.42% id in 331 aa, and to Mycobacterium leprae hypothetical 35.4 kDa protein ML1329 or MLCB2533.25 or B2126_C3_266 SWALL:YK96_MYCLE (SWALL:P54076) (331 aa) fasta scores: E(): 2.8e-19, 30.42% id in 332 aa.
     
 0.764
DIP1768
Conserved hypothetical protein; Similar to Streptomyces coelicolor putative ankyrin-like protein SC6D7.25 TR:Q9RKX3 (EMBL:AL133213) (134 aa) fasta scores: E(): 4.4e-23, 57.36% id in 129 aa, and to Campylobacter jejuni ankyrin-repeat containing protein Cj1386 TR:Q9PMR4 (EMBL:AL139078) (156 aa) fasta scores: E(): 1.2e-10, 39.66% id in 121 aa.
    
 0.742
DIP1243
Conserved hypothetical protein; Similar to Rhodococcus erythropolis ORF11 SWALL:P72265 (EMBL:Z82004) (326 aa) fasta scores: E(): 1.3e-24, 31.42% id in 315 aa, and to Mycobacterium tuberculosis hypothetical 33.8 kDa protein Rv2095c precursor or MT2156 or MTCY49.35c SWALL:YK95_MYCTU (SWALL:Q10704) (316 aa) fasta scores: E(): 3.4e-24, 31.57% id in 304 aa.
 
   
 0.739
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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