STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1249Conserved hypothetical protein; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA. (278 aa)    
Predicted Functional Partners:
DIP1250
Putative M18-family aminopeptidase; Similar to Streptomyces coelicolor probable M18-family aminopeptidase 2 ApeB or SCGD3.02 SWALL:Q9XA76 (EMBL:AL096822) (432 aa) fasta scores: E(): 2.9e-75, 46.31% id in 421 aa, and to Mycobacterium leprae probable M18-family aminopeptidase 2 ApeB or PepC or PepX or ML2213 or MLCB5.29 SWALL:Q50022 (EMBL:U15182) (443 aa) fasta scores: E(): 4.7e-53, 38.78% id in 428 aa.
       0.842
arc
Putative AAA protein family ATPase; Similar to, although shorter in its N-terminal region than Streptomyces coelicolor AAA protein family ATPase Arc SWALL:Q9RJ58 (EMBL:AL132648) (588 aa) fasta scores: E(): 3e-76, 54.14% id in 519 aa, and to, although shorter in its N-terminal region than Mycobacterium leprae putative AAA-family ATPase ML1316 or MLCB2533.12 or A2126A or B2126_C1_167 SWALL:YL15_MYCLE (SWALL:P46509) (609 aa) fasta scores: E(): 2.1e-58, 54.99% id in 531 aa.
 
     0.804
DIP1247
Conserved hypothetical protein; Similar to Rhodococcus erythropolis similar to ORF6 SWALL:Q53081 (EMBL:U26422) (499 aa) fasta scores: E(): 2.2e-72, 48.04% id in 512 aa, and to Frankia spACN14A/ts-r. hypothetical 56.4 kDa protein SWALL:Q9RAW9 (EMBL:AF142435) (505 aa) fasta scores: E(): 3.8e-51, 47.36% id in 494 aa.
 
    0.776
pafA
Conserved hypothetical protein; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side- chain amino group of a substrate lysine.
 
    0.725
DIP1251
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 30.9 kDa protein Rv2119 or MTCY261.15 SWALL:O33254 (EMBL:Z97559) (278 aa) fasta scores: E(): 9e-48, 48.16% id in 272 aa, and to Streptomyces coelicolor hypothetical 31.9 kDa protein SCI41.36 SWALL:Q9RJ55 (EMBL:AL132648) (284 aa) fasta scores: E(): 2.8e-45, 47.34% id in 264 aa.
       0.697
rpmD
Similar to Streptomyces coelicolor 50S ribosomal protein L30 RpmD or SCD31.45 SW:RL30_STRCO (P46789) (60 aa) fasta scores: E(): 2.1e-08, 53.57% id in 56 aa.
   
   0.677
pup
Conserved hypothetical protein; Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
 
     0.663
DIP1398
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 43.2 kDa protein Rv2689c or MT2763 or MTCY05A6.10c TR:O07191 (EMBL:Z96072) (405 aa) fasta scores: E(): 3.4e-27, 40.39% id in 401 aa, and to Streptomyces coelicolor SC10A5.06 protein TR:O54099 (EMBL:AL021529) (458 aa) fasta scores: E(): 1e-20, 31.59% id in 440 aa; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
   
  
 0.660
trmB
Conserved hypothetical protein; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
  
 
 0.604
DIP1244
Conserved hypothetical protein; Similar to Rhodococcus erythropolis ORF10 SWALL:P72264 (EMBL:Z82004) (330 aa) fasta scores: E(): 6.6e-20, 31.42% id in 331 aa, and to Mycobacterium leprae hypothetical 35.4 kDa protein ML1329 or MLCB2533.25 or B2126_C3_266 SWALL:YK96_MYCLE (SWALL:P54076) (331 aa) fasta scores: E(): 2.8e-19, 30.42% id in 332 aa.
       0.598
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.