STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dcuASimilar to Escherichia coli anaerobic C4-dicarboxylate transporter DcuA or GenA or B4138 or Z5743 or ECS5119 SWALL:DCUA_ECOLI (SWALL:P04539) (433 aa) fasta scores: E(): 3.1e-92, 57.33% id in 436 aa, and to Vibrio cholerae C4-dicarboxylate transporter, anaerobic VC2699 SWALL:Q9KNN2 (EMBL:AE004335) (451 aa) fasta scores: E(): 7e-95, 63.15% id in 437 aa. (435 aa)    
Predicted Functional Partners:
aspA
Aspartate ammonia-lyase; Similar to Corynebacterium glutamicum aspartate ammonia-lyase AspA SWALL:ASPA_CORGL (SWALL:Q59200) (526 aa) fasta scores: E(): 1e-151, 75.66% id in 526 aa, and to Escherichia coli aspartate ammonia-lyase AspA or B4139 SWALL:ASPA_ECOLI (SWALL:P04422) (478 aa) fasta scores: E(): 5.2e-121, 67.16% id in 469 aa.
 
  
 0.771
DIP1149
Putative transport protein; Similar to Pasteurella multocida hypothetical protein PM0933 SWALL:Q9CMA1 (EMBL:AE006132) (462 aa) fasta scores: E(): 9.1e-43, 32.62% id in 469 aa, and to Escherichia coli anaerobic C4-dicarboxylate transporter DcuC or B0621 or Z0766 or ECS0660 SWALL:DCUC_ECOLI (SWALL:Q47134) (461 aa) fasta scores: E(): 9.6e-19, 31.76% id in 466 aa.
  
   
 0.725
sdaC
Similar to Escherichia coli serine transporter SdaC or DcrA or B2796 or Z4113 or ECS3656 SW:SDAC_ECOLI (P36559) (429 aa) fasta scores: E(): 4.6e-100, 61.66% id in 420 aa.
  
    0.652
hisG
ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
       0.598
hisE
Similar to Corynebacterium glutamicum phosphoribosyl-ATP pyrophosphatase HisE SWALL:HIS2_CORGL (SWALL:Q9Z471) (87 aa) fasta scores: E(): 3e-23, 73.56% id in 87 aa, to the C-terminal region of Bacillus subtilis histidine biosynthesis bifunctional protein [includes: phosphoribosyl-AMP cyclohydrolase; phosphoribosyl-ATP pyrophosphatase] HisI or HisIE SWALL:HIS2_BACSU (SWALL:O34912) (209 aa) fasta scores: E(): 0.023, 32.53% id in 83 aa, and to the C-terminal region of Escherichia coli histidine biosynthesis bifunctional protein [includes: phosphoribosyl-AMP cyclohydrolase; phosphoribosyl-A [...]
       0.539
DIP1258
Putative hydrolase; Similar to Streptomyces coelicolor putative hydrolase SCI46.01c SWALL:Q9EWH4 (EMBL:AL499607) (233 aa) fasta scores: E(): 4.7e-15, 32.8% id in 189 aa, and to Rhodobacter capsulatus CbbY protein SWALL:CBBY_RHOCA (SWALL:O33513) (227 aa) fasta scores: E(): 1.6e-11, 33.65% id in 205 aa.
       0.531
fhs
Formyltetrahydrofolate synthetase; Similar to Staphylococcus aureus (strain N315) formyltetrahydrofolate synthetase Fhs or SA1553 or SAV1732 SWALL:Q99TD2 (EMBL:AP003134) (555 aa) fasta scores: E(): 1.2e-125, 59.34% id in 551 aa, and to Moorella thermoacetica formate--tetrahydrofolate ligase Fhs SWALL:FTHS_MOOTH (SWALL:P21164) (559 aa) fasta scores: E(): 4.9e-116, 55.57% id in 556 aa.
       0.530
DIP0570
Putative membrane protein; Similar to Escherichia coli O157:H7 putative transport protein ECS4625 TR:BAB38048 (EMBL:AP002566) (561 aa) fasta scores: E(): 3.1e-24, 29.47% id in 536 aa.
  
     0.496
DIP0830
Putative membrane protein; Similar to Escherichia coli hypothetical 58.9 kDa protein YidE or B3685 SW:YIDE_ECOLI (P29211) (553 aa) fasta scores: E(): 1.8e-44, 33.21% id in 554 aa.
  
     0.491
DIP1260
Conserved hypothetical protein; Similar to the plasmid borne Corynebacterium striatum YtpA SWALL:Q9FB56 (EMBL:AF024666) (132 aa) fasta scores: E(): 7.6e-12, 37.19% id in 121 aa.
       0.483
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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