STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bacABacitracin resistance protein; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (282 aa)    
Predicted Functional Partners:
mraY
phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.
    
 0.914
DIP2199
Putative conserved integral membrane protein; Similar to Corynebacterium ammoniagenes Orf2 protein TR:Q9RHY7 (EMBL:AB003155) (163 aa) fasta scores: E(): 6.5e-14, 39.21% id in 153 aa, and to Escherichia coli hypothetical protein YbjG or B0841 SW:YBJG_ECOLI (P75806) (198 aa) fasta scores: E(): 1.9e-06, 32.69% id in 156 aa.
  
 
 0.909
uppS2
Putative undecaprenyl phosphate synthetase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
     
 0.907
DIP1260
Conserved hypothetical protein; Similar to the plasmid borne Corynebacterium striatum YtpA SWALL:Q9FB56 (EMBL:AF024666) (132 aa) fasta scores: E(): 7.6e-12, 37.19% id in 121 aa.
       0.752
cysS2
cysteinyl-tRNA synthetase; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins; Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
       0.752
DIP1263
Putative lipoprotein; Similar to Corynebacterium striatum LppL SWALL:Q9EVJ8 (EMBL:AF024666) (350 aa) fasta scores: E(): 4.3e-35, 34.21% id in 342 aa.
       0.689
DIP1258
Putative hydrolase; Similar to Streptomyces coelicolor putative hydrolase SCI46.01c SWALL:Q9EWH4 (EMBL:AL499607) (233 aa) fasta scores: E(): 4.7e-15, 32.8% id in 189 aa, and to Rhodobacter capsulatus CbbY protein SWALL:CBBY_RHOCA (SWALL:O33513) (227 aa) fasta scores: E(): 1.6e-11, 33.65% id in 205 aa.
 
     0.653
metH
5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
       0.651
pyrD
Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
       0.612
hisE
Similar to Corynebacterium glutamicum phosphoribosyl-ATP pyrophosphatase HisE SWALL:HIS2_CORGL (SWALL:Q9Z471) (87 aa) fasta scores: E(): 3e-23, 73.56% id in 87 aa, to the C-terminal region of Bacillus subtilis histidine biosynthesis bifunctional protein [includes: phosphoribosyl-AMP cyclohydrolase; phosphoribosyl-ATP pyrophosphatase] HisI or HisIE SWALL:HIS2_BACSU (SWALL:O34912) (209 aa) fasta scores: E(): 0.023, 32.53% id in 83 aa, and to the C-terminal region of Escherichia coli histidine biosynthesis bifunctional protein [includes: phosphoribosyl-AMP cyclohydrolase; phosphoribosyl-A [...]
       0.591
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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