STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1276Putative secreted protein; Similar to Mycobacterium tuberculosis hypothetical 41.2 kDa protein Rv1488 or MT1533.2 or MTCY277.09 SWALL:YE88_MYCTU (SWALL:P71768) (381 aa) fasta scores: E(): 1.4e-79, 62.53% id in 363 aa, and to Pyrococcus abyssi stomatin-like protein PAB1324 SWALL:Q9UYE4 (EMBL:AJ248288) (299 aa) fasta scores: E(): 2.7e-35, 42.65% id in 279 aa. (375 aa)    
Predicted Functional Partners:
DIP1277
Putative membrane protein; Similar to Mycobacterium avium MAV145 SWALL:O07404 (EMBL:AF002133) (145 aa) fasta scores: E(): 2.2e-11, 35.25% id in 139 aa, and to Streptomyces coelicolor putative integral membrane protein SC2H12.25 SWALL:Q9K459 (EMBL:AL359215) (146 aa) fasta scores: E(): 7.4e-11, 33.08% id in 136 aa.
 
  
 0.955
ftsH
Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
   
 0.863
DIP1991
Putative membrane protein; Similar to Streptomyces coelicolor putative transmembrane protein SCK7.11c TR:Q9KIM1 (EMBL:AF230489) (312 aa) fasta scores: E(): 4.5e-47, 50.16% id in 301 aa. C-terminal region is similar to Streptococcus pneumoniae hypothetical protein SP2132 TR:AAK76190 (EMBL:AE007502) (335 aa) fasta scores: E(): 8.7e-22, 42.43% id in 304 aa.
      
 0.861
DIP1278
Conserved hypothetical protein; Similar to Streptomyces coelicolor hypothetical 29.4 kDa protein SCC77.24 SWALL:Q9RDD4 (EMBL:AL136503) (274 aa) fasta scores: E(): 1.3e-46, 50.57% id in 259 aa, and to Mycobacterium tuberculosis hypothetical 30.5 kDa protein Rv2033c or MTV018.20 SWALL:O53477 (EMBL:AL021899) (280 aa) fasta scores: E(): 6.7e-37, 46.78% id in 280 aa.
       0.721
DIP2367
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 21.8 kDa protein Rv0038 or MT0043 or MTCY10h4.38 SW:Y038_MYCTU (P71608) (202 aa) fasta scores: E(): 4.4e-28, 43.64% id in 181 aa; Belongs to the UPF0301 (AlgH) family.
   
    0.678
arc
Putative AAA protein family ATPase; Similar to, although shorter in its N-terminal region than Streptomyces coelicolor AAA protein family ATPase Arc SWALL:Q9RJ58 (EMBL:AL132648) (588 aa) fasta scores: E(): 3e-76, 54.14% id in 519 aa, and to, although shorter in its N-terminal region than Mycobacterium leprae putative AAA-family ATPase ML1316 or MLCB2533.12 or A2126A or B2126_C1_167 SWALL:YL15_MYCLE (SWALL:P46509) (609 aa) fasta scores: E(): 2.1e-58, 54.99% id in 531 aa.
   
 
 0.642
DIP1279
Hypothetical protein; No significant database matches.
       0.626
DIP0940
Putative membrane protein; Low similarity to Mycobacterium tuberculosis hypothetical 24.6 kDa protein Rv1100 or MTV017.53 TR:O53448 (EMBL:AL021897) (233 aa) fasta scores: E(): 8e-06, 28.92% id in 204 aa.
   
    0.563
DIP0619
Putative diphtheria toxin repressor 2; Similar to Mycobacterium tuberculosis iron-dependent repressor IdeR or DtxR or Rv2711 or MT2784 or MTCY05A6.32 SW:IDER_MYCTU (Q50495) (230 aa) fasta scores: E(): 1.1e-10, 31.84% id in 201 aa and low similarity to Corynebacterium diphtheriae diphtheria toxin repressor DtxR SW:DTXR_CORDI (P33120) (226 aa) fasta scores: E(): 7.7e-08, 35.08% identity in 114 aa overlap.
   
    0.487
fas
Putative fatty acid synthase; Similar to the N-terminal region of Corynebacterium ammoniagenes fatty acid synthase Fas TR:Q04846 (EMBL:X64795) (3104 aa) fasta scores: E(): 0, 61.33% id in 3018 aa, and to the full length of Mycobacterium tuberculosis fatty acid synthase Rv2524c TR:AAK46907 (EMBL:Z83863) (3069 aa) fasta scores: E(): 1e-197, 51.37% id in 3083 aa, and of Corynebacterium glutamicum 3-oxoacyl-(acyl-carrier-protein) synthase CGL2495 SWALL:Q8NMS0 (EMBL:AP005281) (2993 aa) fasta scores: E(): 0, 67.35% id in 3008 aa.
  
 
 0.454
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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