STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP1277Putative membrane protein; Similar to Mycobacterium avium MAV145 SWALL:O07404 (EMBL:AF002133) (145 aa) fasta scores: E(): 2.2e-11, 35.25% id in 139 aa, and to Streptomyces coelicolor putative integral membrane protein SC2H12.25 SWALL:Q9K459 (EMBL:AL359215) (146 aa) fasta scores: E(): 7.4e-11, 33.08% id in 136 aa. (144 aa)    
Predicted Functional Partners:
DIP1276
Putative secreted protein; Similar to Mycobacterium tuberculosis hypothetical 41.2 kDa protein Rv1488 or MT1533.2 or MTCY277.09 SWALL:YE88_MYCTU (SWALL:P71768) (381 aa) fasta scores: E(): 1.4e-79, 62.53% id in 363 aa, and to Pyrococcus abyssi stomatin-like protein PAB1324 SWALL:Q9UYE4 (EMBL:AJ248288) (299 aa) fasta scores: E(): 2.7e-35, 42.65% id in 279 aa.
 
  
 0.955
DIP1279
Hypothetical protein; No significant database matches.
     
 0.738
cobS
Putative cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
   
    0.730
cobIJ
Similar to Mycobacterium tuberculosis cobalamin biosynthesis protein [includes: precorrin-2 C20-methyltransferase; precorrin-3 methylase] CobIJ or Rv2066 or MT2126 or MTCY49.05 SWALL:COBI_MYCTU (SWALL:Q10677) (508 aa) fasta scores: E(): 3.6e-88, 50.7% id in 495 aa, C-terminal region to Rhodobacter capsulatus precorrin-3 methylase SWALL:O68097 (EMBL:AF010496) (245 aa) fasta scores: E(): 1.1e-34, 48.14% id in 243 aa, and N-terminal region to Pseudomonas aeruginosa precorrin-2 methyltransferase CobI or PA2904 SWALL:Q9HZU3 (EMBL:AE004716) (250 aa) fasta scores: E(): 1.4e-33, 43.3% id in 254 aa.
  
    0.726
DIP1278
Conserved hypothetical protein; Similar to Streptomyces coelicolor hypothetical 29.4 kDa protein SCC77.24 SWALL:Q9RDD4 (EMBL:AL136503) (274 aa) fasta scores: E(): 1.3e-46, 50.57% id in 259 aa, and to Mycobacterium tuberculosis hypothetical 30.5 kDa protein Rv2033c or MTV018.20 SWALL:O53477 (EMBL:AL021899) (280 aa) fasta scores: E(): 6.7e-37, 46.78% id in 280 aa.
       0.721
DIP0831
Putative membrane protein; Similar to Streptomyces coelicolor putative integral membrane protein SCD39.10 TR:Q9F2V1 (EMBL:AL392146) (138 aa) fasta scores: E(): 8.5e-26, 54.26% id in 129 aa.
  
    0.554
DIP1408
Conserved hypothetical protein; Similar, but shorter in its N-terminal region, to Mycobacterium tuberculosis hypothetical 65.8 kDa protein Rv2917 or MT2985 or MTCY338.05 SW:YT17_MYCTU (Q10966) (602 aa) fasta scores: E(): 6.4e-116, 62.39% id in 569 aa, and to Mycobacterium leprae hypothetical 65.2 kDa protein ML1624 or MLCB250.18c SW:YT17_MYCLE (O33011) (596 aa) fasta scores: E(): 8.8e-113, 60.28% id in 569 aa.
  
     0.501
DIP1028
Similar to Streptomyces coelicolor putative MarR-family transcriptional repressor SCE22.22 TR:Q9KYU1 (EMBL:AL355832) (163 aa) fasta scores: E(): 3.5e-17, 37.06% id in 143 aa, and to Escherichia coli transcriptional repressor MprA EmrR or B2684 or Z3985 or ECS3546 SW:MPRA_ECOLI (P24201) (176 aa) fasta scores: E(): 0.0011, 24.79% id in 121 aa.
  
     0.433
nucS
Conserved hypothetical protein; Cleaves both 3' and 5' ssDNA extremities of branched DNA structures; Belongs to the NucS endonuclease family.
  
     0.402
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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